1213770-24-1

Basic information

• Product Name: (4aS,8aS,9aS)-1,1-diphenyloctahydrooxazolo[3,4-a]indol-3(1H)-one
• Synonyms: (4aS,8aS,9aS)-1,1-diphenyloctahydrooxazolo[3,4-a]indol-3(1H)-one
• CAS NO: 1213770-24-1
• Molecular Weight: 333.43
• Mol File: 1213770-24-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4aS,8aS,9aS)-1,1-diphenyloctahydrooxazolo[3,4-a]indol-3(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4aS,8aS,9aS)-1,1-diphenyloctahydrooxazolo[3,4-a]indol-3(1H)-one(1213770-24-1)
• EPA Substance Registry System: (4aS,8aS,9aS)-1,1-diphenyloctahydrooxazolo[3,4-a]indol-3(1H)-one(1213770-24-1)

Safety Data

• Hazardous Substances Data: 1213770-24-1(Hazardous Substances Data)

Upstream product

• 1213770-22-9 (2S,3aS,7aS)-1-ethyl 2-methyl hexahydro-1H-indole-1,2(2H,3H)-dicarboxylate 
• 100-58-3 phenylmagnesium bromide 
• 80875-98-5 (2S,3aS,7aS)-perhydroindole-2-carboxylic acid 

Downstream Products

• 142138-83-8 ((2S,3aS,7aS)-octahydro-1H-indol-2-yl)diphenylmethanol 

Relevant articles and documents

Organocatalyzed regioselective and enantioselective synthesis of 1,4- and 1,2-dihydropyridines

Herein, we introduce one of the first examples of asymmetric organocatalyzed synthesis of 1,2-dihydropyridines, affording enantioselective access to and partially solving regioselectivity challenges in the synthesis of dihydropyridines. We demonstrate that through modification of organocatalysts both 1,2- and 1,4-dihydropyridines (1,2- and 1,4-DHPs) can be obtained with high regioselectivity (ratio of 1,2-DHP/1,4-DHP from 95/5 to 0/100) and enantioselectivity (33% ee for 1,2-DHPs and up to 98% ee for 1,4-DHPs) in good yields (up to 87%).