142138-83-8 Usage
General Description
(2S,3aS,7aS)-Octahydro-α,α-diphenyl-1H-indole-2-methanol is a chemical compound with the molecular formula C20H25NO. It is a derivative of the indole alkaloid family and is commonly used in pharmaceutical research and drug development. (2S,3aS,7aS)- octahydro-α,α-diphenyl-1H-Indole-2-Methanol has potential use in medications for various purposes, including as a sedative, analgesic, or antidepressant. It is also of interest in the field of neuroscience due to its potential effects on the central nervous system. Additionally, it may have applications in the development of new drugs for the treatment of various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 142138-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,2,1,3 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 142138-83:
(8*1)+(7*4)+(6*2)+(5*1)+(4*3)+(3*8)+(2*8)+(1*3)=108
108 % 10 = 8
So 142138-83-8 is a valid CAS Registry Number.
142138-83-8Relevant articles and documents
Organocatalyzed regioselective and enantioselective synthesis of 1,4- and 1,2-dihydropyridines
Le, Truong-Giang,Pham, Hoai-Thu,Martin, James P.,Chataigner, Isabelle,Renaud, Jean-Luc
, p. 2673 - 2684 (2020/08/07)
Herein, we introduce one of the first examples of asymmetric organocatalyzed synthesis of 1,2-dihydropyridines, affording enantioselective access to and partially solving regioselectivity challenges in the synthesis of dihydropyridines. We demonstrate that through modification of organocatalysts both 1,2- and 1,4-dihydropyridines (1,2- and 1,4-DHPs) can be obtained with high regioselectivity (ratio of 1,2-DHP/1,4-DHP from 95/5 to 0/100) and enantioselectivity (33% ee for 1,2-DHPs and up to 98% ee for 1,4-DHPs) in good yields (up to 87%).