1213779-82-8

Basic information

• Product Name: methyl 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylate
• Synonyms: methyl 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylate
• CAS NO: 1213779-82-8
• Molecular Weight: 336.334
• Mol File: 1213779-82-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylate(1213779-82-8)
• EPA Substance Registry System: methyl 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylate(1213779-82-8)

Safety Data

• Hazardous Substances Data: 1213779-82-8(Hazardous Substances Data)

Upstream product

• 21211-07-4 3-chlorobenzo[b]thiophene-2-carboxylic acid methyl ester 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 35212-85-2 3-Amino-benzo[b]thiophene-2-carboxylic acid methyl ester 
• 612-24-8 o-nitrobenzonitrile 
• 34128-30-8 methyl 3-bromobenzothiophene-2-carboxylate 
• 621-82-9 Cinnamic acid 
• 21815-91-8 3-chlorobenzo[b]thiophen-2-carbonyl chloride 

Downstream Products

• 1213779-86-2 3-(4-(trifluoromethyl)phenyl)benzo[b]thiophene-2-carboxylic acid 

Relevant articles and documents

Design and synthesis of condensed thienocoumarins by Suzuki-Miyaura reaction/lactonization tandem protocol

A concise and efficient approach to a series of chromen-4-ones with fused thiophene ring has been developed using the Suzuki-Miyaura reaction of bromothiophene-2- and 3-carboxylates with 2-methoxyboronic acids and subsequent cyclization of prepared alkyl (2-methoxy)aryl thiophene-2- and 3-carboxylates under the action of BBr3/KOtBu. Starting bromothiophenes are easily obtained from corresponding commercially available aminothiophenes by diazotization/bromination reaction.