121386-67-2Relevant academic research and scientific papers
Copper-catalyzed 1,2-addition of nucleophilic silicon to aldehydes: Mechanistic insight and catalytic systems
Kleeberg, Christian,Feldmann, Evgenia,Hartmann, Eduard,Vyas, Devendra J.,Oestreich, Martin
supporting information; experimental part, p. 13538 - 13543 (2012/01/06)
Activation of the Si-B inter-element bond with copper(I) alkoxides produces copper-based silicon nucleophiles that react readily with aldehydes to yield α-silyl alcohols (that is, α-hydroxysilanes) after hydrolysis. Two independent protocols were develope
THE ASYMMETRIC HYDROBORATION OF SIMPLE ALKENYLSILANES: CHIRAL α-SILYLALKYL-BORANES AND ALCOHOLS
Soderquist, John A.,Lee, Shwn-Ji Hwang
, p. 4033 - 4042 (2007/10/02)
The detailed study of the asymmetric hydroboration of various vinylsilanes with monoisopinocampheylborane (IPCBH2) is presented.In all cases, β substitution on the vinylsilane gives monomeric dialkylborane adducts with the boryl group α to the silicon.These studies shown that the larger the groups on silicon are, the more positive the influence on the enatioselectivity of the process.Moderate asymmetric induction (24-40percent) is observed only for vinyl silanes wich contain a substituent trans to the silicon.A model for the asymmetric hydroboration of alkenes with this reagent is proposed.The complete charactarization of the borane intermediates was achieved employing NMR (11B, 13C, 1H, 29Si).
GENERATION OF THIOALDEHYDES VIA FLUORIDE INDUCED ELIMINATION OF Α-SILYLDISULFIDES
Krafft, Grant A.,Meinke, Peter T.
, p. 1947 - 1950 (2007/10/02)
A mild, efficient and general method for the generation of reactive thioaldehydes from α-silyldisulfides is described.
