121394-28-3Relevant academic research and scientific papers
Selenium-catalyzed oxidative c(sp2)-h amination of alkenes exemplified in the expedient synthesis of (Aza-)indoles
Ortgies, Stefan,Breder, Alexander
supporting information, p. 2748 - 2751 (2015/06/16)
A new selenium-catalyzed protocol for the direct, intramolecular amination of C(sp2)-H bonds using N-fluorobenzenesulfonimide as the terminal oxidant is reported. This method enables the facile formation of a broad range of diversely functionalized indoles and azaindoles derived from easily accessible ortho-vinyl anilines and vinylated aminopyridines, respectively. The procedure exploits the pronounced carbophilicity of selenium electrophiles for the catalytic activation of alkenes and leads to the formation of C(sp2)-N bonds in high yields and with excellent functional group tolerance.
Aminostilbazole derivative and medicine
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, (2008/06/13)
The invention relates to an aminostilbazole derivative of the following formula or a hydrate thereof, and a salt thereof. STR1 wherein R1 and R2 each represents hydrogen etc.; R3, R4, R13, and R14 each represents hydrogen, C1-3 acyl, halogen, hydroxy etc.; R5 represents hydrogen or hydroxy-substituted C1-3 alkyl etc.; R6 represents benzenesulfonyl substituted by C1-3 alkoxy etc.; ring Y represents phenyl etc.; ring Z represents 4-pyridyl, its oxide etc. The compound is useful or the treatment of various malignant tumors.
Antiulcer Agents. 4. Conformational Considerations and the Antiulcer Activity of Substituted Imidazopyridines and Related Analogues
Kaminski, James J.,Puchalski, Chester,Solomon, Daniel M.,Rizvi, Razia K.,Conn, David J.,et al.
, p. 1686 - 1700 (2007/10/02)
Definition of the interrelationship between the conformational characteristics of a series of substituted imidazopyridines and their antiulcer activity was investigated by examining the conformational properties of 3-cyano-2-methyl-8-(phenylmethoxy
