121402-70-8

Upstream product

• 139618-41-0 (2S,3aS,4R,7S,7aR)-2-Methyl-2-p-tolyl-2,3,3a,4,7,7a-hexahydro-4,7-methano-inden-1-one 
• 15106-88-4 di(p-tolyl)zinc 
• 121402-60-6 (2RS,3S,4S)-4-benzyloxycarbonyl-4-hydroxy-2-methoxycarbonyl-3-methyl-3-p-tolyl-1-cyclopentanone 
• 121468-99-3 (3S,4S)-4-benzyloxycarbonyl-4-hydroxy-3-methyl-3-p-tolyl-1-cyclopentanone 
• 118204-77-6 (+)-4-benzyloxycarbonyl-4-hydroxy-2-methoxycarbonyl-3-methylcyclopent-2-en-1-one 
• 121402-64-0 (1RS,3S,4S)-4-hydroxymethyl-3-methyl-3-p-tolyl-1,4-cyclopentanediol 
• 121402-65-1 (2S,4RS)-4-hydroxy-2-methyl-2-p-tolyl-1-cyclopentanone 
• 917-54-4 methyllithium 
• 121402-69-5 (S)-(+)-5-methyl-5-(4-methylphenyl)cyclopent-2-en-1-one 

Downstream Products

• 109334-10-3 (4R)-3,4-dimethyl-4-(p-tolyl)-2-cyclopentenone 

Relevant academic research and scientific papers

ENANTIOCONTROLLED SYNTHESES OF THE CUPARENE SESQUITERPENES, (-)-HERBERTENE, (+)-β-CUPARENONE, (-)-DEBROMOAPLYSIN, AND (-)-APLYSIN

Enantiocontrolled syntheses of the Cuparene sesquiterpenes, (-)-herbertene, (+)-cuparenone, (-)-debromoaplysin, and (-)-aplysin, have been achieved starting from the optically active tricyclic dienone by employing a Fischer indolization reaction under non-acidic conditions as the key step.

Formal synthesis of (-)-α- and (+)-β-Cuparenones, Cuparene, and Laurene

This paper describes formal synthesis of the title compounds from easily prepared chiral synthon (+)-5.One of the structural features of the cuparene family is the presence of vicinal quaternary carbons on the five-membered ring.The quaternary carbon with