15106-88-4

Basic information

• Product Name: Zinc, bis(4-methylphenyl)-
• CAS NO: 15106-88-4
• Molecular Formula: C14H14Zn
• Molecular Weight: 247.655
• Mol File: 15106-88-4.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Zinc, bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Zinc, bis(4-methylphenyl)-(15106-88-4)
• EPA Substance Registry System: Zinc, bis(4-methylphenyl)-(15106-88-4)

Safety Data

• Hazardous Substances Data: 15106-88-4(Hazardous Substances Data)

Upstream product

• 106-38-7 para-bromotoluene 
• 7699-45-8 zinc dibromide 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 7646-85-7 zinc(II) chloride 
• 2417-95-0 p-tolyllithium 
• 1201594-37-7 (4-[trifluoromethyl]phenyl) N,N-dimethylsulfamate 
• 90252-89-4 p-tolylzinc(II) chloride 
• 624-31-7 4-tolyl iodide 
• 696-61-7 4-tolylmagnesium chloride 

Downstream Products

• 5440-76-6 (4-methylphenyl)diphenylmethanol 
• 99-94-5 p-Toluic acid 
• 134-84-9 4-Methylbenzophenone 
• 2431-00-7 p-methylbenzil 
• 1283129-19-0 2,3,4,6-tetra-O-pivaloyl 1-(4-tolyl)-1-deoxy-β-D-glucopyranose 
• 71947-05-2 4-(4-methylbenzyl)benzonitrile 
• 27331-34-6 1-(4-methylphenyl)naphthalene 
• 50670-50-3 p-(p-tolyl)benzonitrile 
• 59115-49-0 2-(p-tolyl)naphthalene 
• 91543-45-2 3-hydroxy-2-phenyl-3-(p-tolyl)isoindolin-1-one 
• 66865-75-6 4-methyl-α,α-difluorotoluene 
• 311819-16-6 (CH₃C₆H₄)3Zn^(1-)*K⁽¹⁺⁾=(CH₃C₆H₄)3ZnK 
• 100655-03-6 [W(CH₃C₆H₄CHC₆H₄CH₃)(CO)2(C₅H₅)] 
• 138667-87-5 (4-methylphenyl)trioxorhenium 

Relevant articles and documents

Atom-efficient transition-metal-free arylation ofN,O-acetals using diarylzinc reagents through Zn/Zn cooperativity

Exploiting the cooperative action of Lewis acid Zn(C6F5)2with diarylzinc reagents, the efficient arylation ofN,O-acetals to access diarylmethylamines is reported. Reactions take place under mild reaction conditions without the need for transtion-metal catalysis. Mechanistic investigations have revealed that Zn(C6F5)2not only acts as a Lewis acid activator, but also enables the regeneration of nucleophilic ZnAr2species, allowing a limiting 50 mol% to be employed.

Three-Component Difunctionalization of Cyclohexenyl Triflates: Direct Access to Versatile Cyclohexenes via Cyclohexynes

Difunctionalization of strained cyclic alkynes presents a powerful strategy to build richly functionalized cyclic alkenes in an expedient fashion. Herein we disclose an efficient and flexible approach to achieve carbohalogenation, dicarbofunctionalization, aminohalogenation and aminocarbonation of readily available cyclohexenyl triflates. We have demonstrated the novel use of zincate base/nucleophile system for effective formation of key cyclohexyne intermediates and selective addition of various carbon and nitrogen nucleophiles. Importantly, leveraging the resulting organozincates enables the incorporation of a broad range of electrophilic partners to deliver structurally diverse cyclohexene motifs. The importance and utility of this method is also exemplified by the modularity of this approach and the ease in which even highly complex polycyclic scaffolds can be accessed in one step.

Cobalt-Catalyzed α-Arylation of Substituted α-Bromo α-Fluoro β-Lactams with Diaryl Zinc Reagents: Generalization to Functionalized Bromo Derivatives

A cobalt-catalyzed cross-coupling of α-bromo α-fluoro β-lactams with diarylzinc or diallylzinc reagents is herein disclosed. The protocol proved to be general, chemoselective and operationally simple allowing the C4 functionalization of β-lactams. The substrate scope was expanded to α-bromo lactams and amides, α-bromo lactones and esters as well as N- and O-containing heterocycles.