121405-41-2Relevant academic research and scientific papers
Synthesis and Biological Activity of Pyrrolopyrimidines
Dave, Chaitanya G.,Shah, P. R.,Upadhyaya, S. P.,Gandhi, T. P.,Patel, R. B.
, p. 778 - 780 (2007/10/02)
2-Amino-3-cyanopyrroles (I) on reaction with formamide and carbon disulphide in pyridine give 4-amino-5,6,7-trisubstituted-7H-pyrrolopyrimidines (II) and 5,6,7-trisubstitutedpyrrolopyrimidine-2,4(1H,3H)-dithiones (III), respectively. 2,4-Bis(methylmercapto)-5,6,7-trisubstitutedpyrrolopyrimidines (IV) have been prepared by reacting III with dimethyl sulphate in basic medium.Structures of the synthesized compounds have been established by elemental analyses and spectral data.Some of them have been screened for their antibacterial, analgesic, antiinflammatory, antihistaminic, anticholinergic, anticonvulsant and antihypertensive activities.
