1214265-44-7

Basic information

• Product Name: C₁₈H₂₀F₂N₆O₃
• Synonyms: C₁₈H₂₀F₂N₆O₃
• CAS NO: 1214265-44-7
• Molecular Weight: 406.392
• Mol File: 1214265-44-7.mol

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₀F₂N₆O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₀F₂N₆O₃(1214265-44-7)
• EPA Substance Registry System: C₁₈H₂₀F₂N₆O₃(1214265-44-7)

Safety Data

• Hazardous Substances Data: 1214265-44-7(Hazardous Substances Data)

Upstream product

• 1214265-43-6 C₁₉H₂₃F₂N₃O₆S 
• 129321-60-4 5,8-dioxa-10-azadispiro[2.0.44.33]undecane 
• 1214265-36-7 C₁₄H₁₆F₂N₂O₂ 
• 1214265-35-6 3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)-nitrobenzene 
• 1214265-27-6 (S)-N-{{3-[3,5-difluoro-4-(7-hydroxy-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl}acetamide 
• 1214265-42-5 (S)-N-{{3-[3,5-difluoro-4-(7-oxo-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl}acetamide 
• 1214265-38-9 (R)-{N-3-[3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methanol 
• 1214265-37-8 N-carbobenzyloxy-[3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)phenyl]aniline 
• 1214265-40-3 (R)-{N-3-[3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl azide 
• 1214265-39-0 (R)-{N-3-[3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl methanesulfonate 
• 1214265-41-4 (S)-N-{{3-[3,5-difluoro-4-(7,7-ethylenedioxy-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl}acetamide 
• 66684-58-0 3,4,5-trifluoronitrobenzene 

Downstream Products

• 1214265-34-5 (S)-N-{{3-[3,5-difluoro-4-(7-amino-5-azaspiro[2,4]heptan-5-yl)phenyl]-2-oxo-5-oxazolidinyl}methyl}acetamide 

Relevant articles and documents

Novel oxazolidinone derivative with difluorophenyl moiety, pharmaceutically acceptable salt thereof, preparation method thereof and antibiotic composition containing the same as an active ingredient

Novel oxazolidinone derivatives with a difluorophenyl moiety, represented by Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition containing the same as an active ingredient are provided. Exhibiting potent inhibitory activity against Gram-positive bacteria including Haemophilus influenza and Coagulase negative staphylococci and resistant bacteria including vancomycin-resistant enterococci (VRE), the pharmaceutical composition is useful as an antibiotic. (wherein, R is as defined in the specification)

NOVEL OXAZOLIDINONE DERIVATIVE WITH DIFLUOROPHENYL MOIETY, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF AND ANTIBIOTIC COMPOSITION COMPRISING THE SAME AS ACTIVE INGREDIENT

Novel oxazolidinone derivatives with a difluorophenyl moiety, represented by Chemical Formula 1, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient are provided. Exhibiting potent inhibitory activity against Gram-positive bacteria including Haemophilus influenza and Coagulase negative staphylococci and resistant bacteria including vancomycin-resistant en- terococci (VRE), the pharmaceutical composition is useful as an antibiotic.