121443-95-6

Basic information

• Product Name: 1-Methyl-2-<(1S)-1-(2,6-dichlorophenyl)ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 1-Methyl-2-<(1S)-1-(2,6-dichlorophenyl)ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 121443-95-6
• Molecular Weight: 380.314
• Mol File: 121443-95-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Methyl-2-<(1S)-1-(2,6-dichlorophenyl)ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-2-<(1S)-1-(2,6-dichlorophenyl)ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(121443-95-6)
• EPA Substance Registry System: 1-Methyl-2-<(1S)-1-(2,6-dichlorophenyl)ethyl>-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline(121443-95-6)

Safety Data

• Hazardous Substances Data: 121443-95-6(Hazardous Substances Data)

Upstream product

• 128592-47-2 N-[(S)-1-(2,6-Dichloro-phenyl)-ethyl]-N-[2-(3,4-dimethoxy-phenyl)-ethyl]-formamide 
• 121443-83-2 (S)-N-<2-(3,4-Dimethoxyphenyl)ethyl>-1-(2,6-dichlorophenyl)ethylamine 
• 74-83-9 methyl bromide 

Relevant articles and documents

Diastereoselective addition of organometallic reagents to chiral iminium ions: Synthesis of (S)-(+)-cryptostyline I

Iminium ion 2c participates in stereoselective nucleophilic addition reactions with Grignard reagents. Analysis of the products from reaction of 5-hexenylmagnesium bromide with iminium ion 2a suggests that these reactions proceed by a polar (two electron) mechanism. The utility of this chemistry is demonstrated in a stereo specific synthesis of (5)-(+)-cryptostylina I.