1214720-61-2Relevant academic research and scientific papers
Polyphosphoric acid-mediated, One-Pot, novel reactions to build polymethoxyarylnaphthalene lignans
Zhao, Guilong,Zhan, Fuxu,Wang, Zhifeng,Xu, Weiren,Wang, Yuli,Liu, Wei,Tang, Lida,Wang, Jianwu
, p. 351 - 360 (2010)
The one-pot reaction of succinic anhydride with 1,2-dimethoxybenzene furnished two structurally complicated polymethoxyarylnaphthalene lignans, polymethoxyarylnaphthol 1 as the minor product and polymethoxynaphtho[1,2-b] oxacycloheptatrienone 2 as the major product, in the presence of a small amount of polyphosphoric acid (PPA) as catalyst at 140°C and yielded 2 as a single product in good yield when a large amount of PPA as solvent was employed at 60-80°C. The novel structures of 1 and 2 were elucidated from 1H NMR, 13C NMR, infrared (IR), and Electrospray ionization-mass spectrometry (ESI-MS) and further confirmed by X-ray diffractions. The possible mechanisms for the formation of 1 and 2 were also proposed.
