1214935-71-3Relevant academic research and scientific papers
Glycodynamers: Dynamic polymers bearing oligosaccharides residues - Generation, structure, physicochemical, component exchange, and lectin binding properties
Ruff, Yves,Buhler, Eric,Candau, Sauveur-Jean,Kesselman, Ellina,Talmon, Yeshayahu,Lehn, Jean-Marie
, p. 2573 - 2584 (2010)
Dynamic glycopolymers have been generated by polycondensation through acylhydrazone formation between components bearing lateral bioactive oligosaccharide chains. They have been characterized as bottlebrush type by cryo-TEM and SANS studies. They present remarkable fluorescence properties whose emission wavelengths depend on the constitution of the polymer and are tunable by constitutional modification through exchange/Incorporation of components, thus also demonstrating their dynamic character. Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated.
