1215-15-2Relevant academic research and scientific papers
Choline chloride and urea based eutectic solvents: Effective catalytic systems for the Knoevenagel condensation reactions of substituted acetonitriles
Liu, Shuo,Ni, Yuxiang,Wei, Wenjing,Qiu, Fangli,Xu, Songlin,Ying, Anguo
, p. 186 - 188 (2014)
The Knoevenagel condensation of aromatic aldehydes with active methylene compounds such as malononitrile, ethyl cyanoacetate, benzimidazole-2- acetonitrile and benzothiazole-2-acetonitrile proceeded very smoothly, in a reusable and cheap choline chloride and urea based deep eutectic solvents. Both reaction time and yield are satisfactory. The advantages of this catalyst are that it is readily available, biodegradable, non-toxic, low cost and is recyclable.
Ionic tagged amine supported on magnetic nanoparticles: Synthesis and application for versatile catalytic Knoevenagel condensation in water
Ying, Anguo,Qiu, Fangli,Wu, Chenglin,Hu, Huanan,Yang, Jianguo
, p. 33175 - 33183 (2014/08/18)
Propylamine modified with imidazolium ionic moiety grafted onto magnetic nanoparticles (MNPs) was prepared and evaluated as a catalyst for Knoevenagel condensation in water at room temperature. The catalyst was efficient in the reaction to give the condensation products in good yields. It is worth noting that the ionic-tagged catalyst performed significantly better than its ionic tag-free counterpart. Finally, the catalyst could be reused for 8 times with a slight loss in its catalytic activity. the Partner Organisations 2014.
PHENANTHROINDOLIZIDINE COMPOUND AND NF B INHIBITOR CONTAINING SAME AS ACTIVE INGREDIENT
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Page/Page column 16, (2011/08/08)
A novel compound having an excellent NFκB inhibitory effect is provided and specifically disclosed is a compound represented by the following formula (1) or a salt thereof: wherein, R1 represents a hydrogen atom, a lower alkyl group, a lower al
