1215003-91-0

Basic information

• Product Name: 2-[2-(3-acetylphenyl)phenyl]pyridine
• Synonyms: 2-[2-(3-acetylphenyl)phenyl]pyridine
• CAS NO: 1215003-91-0
• Molecular Weight: 273.334
• Mol File: 1215003-91-0.mol

Chemical Properties

• CAS DataBase Reference: 2-[2-(3-acetylphenyl)phenyl]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[2-(3-acetylphenyl)phenyl]pyridine(1215003-91-0)
• EPA Substance Registry System: 2-[2-(3-acetylphenyl)phenyl]pyridine(1215003-91-0)

Safety Data

• Hazardous Substances Data: 1215003-91-0(Hazardous Substances Data)

Upstream product

• 1008-89-5 2-phenylpyridine 
• 99-02-5 3'-Chloroacetophenone 

Relevant articles and documents

RuCi3 xH2O-catalyzed direct arylation of arenes with aryl chlorides in the presence of triphenylphosphine

A study was conducted to demonstrate the RuCl3·xH 2O catalytic system for direct arylation of arenes with aryl chlorides. The phenylation of benzo[h]quinoline with chlorobenzene was investigated under preliminary studies. The reaction of benzo[h]quinoline and chlorobenzene N-methyl-2-pyrrolidone (NMP) formed Ph as the only product in 86-93% yields at 120-130 8C in the presence of K2CO3 using 5 mol% RuCl3·xH2O and 10 mol% PPh3. It was observed that the presence of an excess of ligand did not affect formation of Ph, while sub-stoichiometric ligand amounts led to a reduced conversion for benzo[h]quinoline. The arylation and benzylation of benzo[h]quinoline with various aryl chlorides was also investigated under the study.

Hydrophilic (ν6-Arene)-Ruthenium(II) Complexes with P-OH ligands as catalysts for the isomerization of allylbenzenes and C-H bond arylation reactions in water

Half-sandwich ruthenium(II) complexes containing ν6-coordinated 3-phenylpropanol and phosphinous-acid-type ligands, namely, [RuCl2(ν6-C6H5CH2CH2CH2OH){P(OH)R2}] (R = Me (2a), Ph (2b), 4-C6H4CF3 (2c), 4-C6H4OMe (2d), OMe (2e), OEt (2f), and OPh (2g), have been synthesized in 44-88% yield by reacting [RuCl2{ν6:κ1(O)-C6H5CH2CH2CH2OH}] (1) with the appropriate pentavalent phosphorus oxide R2P(═O)H. The structure of [RuCl2(ν6-C6H5CH2CH2CH2OH){P(OH)Me2}] (2a) was unequivocally confirmed by X-ray diffraction methods. Compounds 2a-g proved to be catalytically active in the isomerization of allylbenzenes into the corresponding (1-propenyl)benzene derivatives employing water as the sole reaction solvent, with [RuCl2(ν6-C6H5CH2CH2CH2OH){P(OH)(OPh)2}] (2g) showing the best performance and a broad substrate scope (73-93% isolated yields with E/Z ratios around 90:10 employing 1 mol % of 2g and 3 mol % of K2CO3, and performing the catalytic reactions at 80 °C for 4-24 h). The results herein presented show for the first time the utility of phosphinous acids as auxiliary ligands for metal-catalyzed olefin isomerization processes, reactions in which a cooperative role for the P - OH unit is proposed. On the other hand, the utility of complexes 2a-g as catalysts for ortho-arylation reactions of 2-phenylpyridine in water is also briefly discussed.

Combination of RuCl3·: X H2O with PEG-a simple and recyclable catalytic system for direct arylation of heteroarenes via C-H bond activation

A simple and recyclable catalytic system for direct arylation of heteroarenes via C-H bond activation was developed with a relatively inexpensive RuCl3·xH2O as a catalyst and PEG-400 as a green medium without any additive or ligand.

Acetamide as cocatalyst for the nitrogen-directed coupling of arenes with aryl chlorides through ruthenium-catalyzed c-h activation

A simple and highly efficient method for the cross-coupling of aromatics by C-H activation is described. Acetamide was found to be an effective cocatalyst for this generally applicable ruthenium(II)-catalyzed direct arylation reaction. A wide range of dea