1215072-60-8

Basic information

• Product Name: 2-(4-Methoxyphenyl)pyridin-4-aMine
• Synonyms: 2-(4-Methoxyphenyl)pyridin-4-aMine
• CAS NO: 1215072-60-8
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.23648
• Mol File: 1215072-60-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Methoxyphenyl)pyridin-4-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)pyridin-4-aMine(1215072-60-8)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)pyridin-4-aMine(1215072-60-8)

Safety Data

• Hazardous Substances Data: 1215072-60-8(Hazardous Substances Data)

Usage

Type of compound

chemical compound

Derivative

pyridine (heterocyclic organic compound)

Structural feature

pyridine ring with a 4-methoxyphenyl group attached at the 2-position

Usage

intermediate in the pharmaceutical industry for the synthesis of various drugs and pharmaceuticals

Potential properties

antioxidant and antiproliferative

Precautions

potential toxicity and health hazards, should be handled and used with caution

Upstream product

• 14432-12-3 4-Amino-2-chloropyridine 
• 5720-07-0 4-methoxyphenylboronic acid 

Downstream Products

• 856851-28-0 4-chloro-2-(4-methoxyphenyl)pyridine 

Relevant articles and documents

FNEW ACTIVATORS OF SIRT1 ENZYME FOR THE TREATMENT OF CARDIOVASCULAR AND CARDIOMETABOLIC PATHOLOGIES

This invention describes a class of compounds able to activate the human SIRT1 enzyme and regulate many metabolic functions. This invention relates to compounds that can be employed in medical applications, specifically for the treatment or prevention of cardiometabolic diseases, such as diabetes, and of cardiovascular disorders, such as coronaropathy, heart failure and atherosclerosis.

An active, general, and long-lived palladium catalyst for cross-couplings of deactivated (hetero)aryl chlorides and bromides with arylboronic acids

An active, general, and long-lived palladium catalyst for Suzuki-Miyaura reactions of aryl and heteroaryl chlorides deactivated by steric hindrance, electron richness, and coordinating functional groups is reported. In reactions of arylbromide bearing two o-tert-butyl substituents, C(sp3)-H arylation of the tert-butyl group, rather than the Suzuki-Miyaura reaction, proceeded in excellent yield. The key to the success of the reactions was the development of biphenylene-substituted dicyclohexylruthenocenylphosphine (CyR-Phos) as a supporting ligand.