1215085-92-9 Usage
Uses
Used in Pharmaceutical Industry:
GLPG 0492 is used as a therapeutic agent for muscle wasting conditions due to its ability to reduce muscle loss while sparing reproductive tissues. It has been shown to increase levator ani muscle weight, improve twitch tension in isolated diaphragm strips, and reverse immobilization-induced muscle atrophy in mouse models.
Used in Muscular Dystrophy Treatment:
GLPG 0492 is used as a potential treatment for muscular dystrophy, as it has been demonstrated to decrease gastrocnemius muscle fibrosis in the exercised-mdx mouse model of the disease when administered at a dose of 30 mg/kg.
Used in Athletic Performance Enhancement:
GLPG 0492 is used as a performance-enhancing substance for athletes, as it has been shown to increase the total distance run in a treadmill test, suggesting potential benefits for endurance and muscle function. However,
Check Digit Verification of cas no
The CAS Registry Mumber 1215085-92-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,5,0,8 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1215085-92:
(9*1)+(8*2)+(7*1)+(6*5)+(5*0)+(4*8)+(3*5)+(2*9)+(1*2)=129
129 % 10 = 9
So 1215085-92-9 is a valid CAS Registry Number.
1215085-92-9Relevant academic research and scientific papers
Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator
Nique, Francois,Hebbe, Severine,Triballeau, Nicolas,Peixoto, Christophe,Lefrancois, Jean-Michel,Jary, Helene,Alvey, Luke,Manioc, Murielle,Housseman, Christopher,Klaassen, Hugo,Van Beeck, Kris,Guedin, Denis,Namour, Florence,Minet, Dominque,Van Der Aar, Ellen,Feyen, Jean,Fletcher, Stephen,Blanque, Roland,Robin-Jagerschmidt, Catherine,Deprez, Pierre
, p. 8236 - 8247,12 (2020/09/15)
Structural modification performed on a 4-methyl-4-(4-hydroxyphenyl) hydantoin series is described which resulted in the development of a new series of 4-(hydroxymethyl)diarylhydantoin analogues as potent, partial agonists of the human androgen receptor. T
NOVEL IMIDAZOLIDINE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS
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Page/Page column 51, (2010/04/06)
Novel compounds are disclosed that have a Formula represented by the following: wherein X, R1, R2a, R2b, R2c, R3a R3b, R4a, R4b, R4c, and ml are as describe
