1215106-19-6

Basic information

• Product Name: 3-(3-nitropyridin-4-yl)benzoic acid
• Synonyms: 3-(3-nitropyridin-4-yl)benzoic acid
• CAS NO: 1215106-19-6
• Molecular Weight: 244.207
• Mol File: 1215106-19-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(3-nitropyridin-4-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-nitropyridin-4-yl)benzoic acid(1215106-19-6)
• EPA Substance Registry System: 3-(3-nitropyridin-4-yl)benzoic acid(1215106-19-6)

Safety Data

• Hazardous Substances Data: 1215106-19-6(Hazardous Substances Data)

Upstream product

• 25487-66-5 3-Carboxyphenylboronic acid 
• 13091-23-1 4-chloro-3-nitropyridine 

Downstream Products

• 1215106-20-9 3-(3-nitropyridin-4-yl)-N-(2-phenylpropan-2-yl)benzamide 
• 1215106-26-5 1-amino-3-(N-(2-hydroxyethyl)methylsulfonamido)-4-(3-(2-phenylpropan-2-ylcarbamoyl)phenyl)pyridinium 2,4,6-trimethylbenzenesulfonate 
• 1215106-23-2 3-(3-(N-(2-(tert-butyldimethylsilyloxy)ethyl)methylsulfonamido)pyridin-4-yl)-N-(2-phenylpropan-2-yl)benzamide 
• 1215106-22-1 3-(3-(methylsulfonamido)pyridin-4-yl)-N-(2-phenylpropan-2-yl)benzamide 
• 1215106-21-0 3-(3-aminopyridin-4-yl)-N-(2-phenylpropan-2-yl)benzamide 

Relevant articles and documents

Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis

Selective chemistry that modifies the structure of DNA and RNA is essential to understanding the role of epigenetic modifications. We report a visible-light-activated photocatalytic process that introduces a covalent modification at a C(sp3)-H bond in the methyl group of N6-methyl deoxyadenosine and N6-methyl adenosine, epigenetic modifications of emerging importance. A carefully orchestrated reaction combines reduction of a nitropyridine to form a nitrosopyridine spin-trapping reagent and an exquisitely selective tertiary amine-mediated hydrogen-atom abstraction at the N6-methyl group to form an α-amino radical. Cross-coupling of the putative α-amino radical with nitrosopyridine leads to a stable conjugate, installing a label at N6-methyl-adenosine. We show that N6-methyl deoxyadenosine-containing oligonucleotides can be enriched from complex mixtures, paving the way for applications to identify this modification in genomic DNA and RNA.

COMPOUNDS FOR THE TREATMENT OF HEPATITIS C

The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.