1215174-25-6Relevant articles and documents
Remote functionalization of SCH 39166: Discovery of potent and selective benzazepine dopamine D1 receptor antagonists
Sasikumar,Burnett, Duane A.,Greenlee, William J.,Smith, Michelle,Fawzi, Ahmad,Zhang, Hongtao,Lachowicz, Jean E.
scheme or table, p. 832 - 835 (2010/09/15)
A series of novel benzazepine derived dopamine D1 antagonists have been discovered. These compounds are highly potent at D1 and showed excellent selectivity over D2 and D4 receptors. SAR studies revealed that a