121573-36-2

Basic information

• Product Name: 10,10-difluorothromboxane A2
• Synonyms: 10,10-difluorothromboxane A2
• CAS NO: 121573-36-2
• Molecular Formula: C20H30 F2 O5
• Molecular Weight: 388.45
• Mol File: 121573-36-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 495.8°C at 760 mmHg
• Flash Point: 253.7°C
• Appearance: /
• Density: 1.19g/cm³
• Vapor Pressure: 6.56E-12mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: 10,10-difluorothromboxane A2(CAS DataBase Reference)
• NIST Chemistry Reference: 10,10-difluorothromboxane A2(121573-36-2)
• EPA Substance Registry System: 10,10-difluorothromboxane A2(121573-36-2)

Safety Data

• Hazardous Substances Data: 121573-36-2(Hazardous Substances Data)

Usage

Chemical structure

10,10-difluorothromboxane A2 is a synthetic chemical compound with a structure similar to thromboxane A2, a lipid molecule involved in blood clotting and vasoconstriction.

Fluorine atoms

It contains two fluorine atoms at the 10th position, which alters its biological activity and pharmacological properties.

Biological activity

The presence of fluorine atoms in 10,10-difluorothromboxane A2 changes its biological activity compared to thromboxane A2.

Pharmacological properties

The unique structure of 10,10-difluorothromboxane A2 results in different pharmacological properties compared to thromboxane A2.

Platelet aggregation

10,10-difluorothromboxane A2 has been studied for its potential role in platelet aggregation, a process involved in blood clotting.

Cardiovascular health

The compound has been investigated for its potential effects on cardiovascular health, as thromboxane A2 plays a role in vasoconstriction and blood clotting.

Inflammatory processes

10,10-difluorothromboxane A2 has been studied in the context of inflammatory processes, as thromboxane A2 is involved in these processes.

Research tool

The unique structure and properties of 10,10-difluorothromboxane A2 make it a valuable tool for understanding the mechanisms of thromboxane A2 signaling.

Drug development

10,10-difluorothromboxane A2 is a useful compound for developing new therapeutic drugs targeting the thromboxane A2 pathway.

Applications

The compound is particularly relevant for research and drug development in the field of cardiovascular and inflammatory diseases.

InChI:InChI=1/C20H30F2O5/c1-2-3-6-9-14(23)12-13-16-15(10-7-4-5-8-11-17(24)25)18-20(21,22)19(26-16)27-18/h4,7,12-16,18-19,23H,2-3,5-6,8-11H2,1H3,(H,24,25)/b7-4-,13-12+/t14-,15+,16+,18-,19-/m0/s1

Upstream product

• 121573-30-6 (Z)-7-[(1R,3R,4R,5R)-7,7-Difluoro-3-((E)-3-oxo-oct-1-enyl)-2,6-dioxa-bicyclo[3.1.1]hept-4-yl]-hept-5-enoic acid methyl ester 
• 121573-28-2 (Z)-7-((1R,3S,4R,5R)-7,7-Difluoro-3-hydroxymethyl-2,6-dioxa-bicyclo[3.1.1]hept-4-yl)-hept-5-enoic acid methyl ester 
• 121573-29-3 (Z)-7-((1R,3S,4R,5R)-7,7-Difluoro-3-formyl-2,6-dioxa-bicyclo[3.1.1]hept-4-yl)-hept-5-enoic acid methyl ester 
• 121573-22-6 Acetic acid (1R,3S,4R,5R)-7,7-difluoro-4-methanesulfonyloxymethyl-2,6-dioxa-bicyclo[3.1.1]hept-3-ylmethyl ester 
• 121573-23-7 Acetic acid (1R,3S,4R,5R)-4-cyanomethyl-7,7-difluoro-2,6-dioxa-bicyclo[3.1.1]hept-3-ylmethyl ester 
• 121573-25-9 ((1R,3S,4R,5R)-7,7-Difluoro-3-hydroxymethyl-2,6-dioxa-bicyclo[3.1.1]hept-4-yl)-acetic acid methyl ester 
• 121573-20-4 Acetic acid (1R,3S,4R,5R)-7,7-difluoro-4-hydroxymethyl-2,6-dioxa-bicyclo[3.1.1]hept-3-ylmethyl ester 
• 121573-24-8 (1R,3R,4R,5S)-4-(oxoethyl)-5-(hydroxymethyl)-7,7-difluoro-2,6-dioxabicyclo<3.1.1>heptane 
• 75910-96-2 Dimethyl 2-oxoheptylphosphonate anion 
• 17814-85-6 (4-carboxybutyl)triphenylphosphonium bromide 
• 121573-32-8 (Z)-7-[(1R,3R,4R,5R)-7,7-Difluoro-3-((E)-(S)-3-hydroxy-oct-1-enyl)-2,6-dioxa-bicyclo[3.1.1]hept-4-yl]-hept-5-enoic acid methyl ester 

Relevant articles and documents

Synthesis of 10,10-difluorothromboxane A2, a potent and chemically stable thromboxane agonist

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