1217271-36-7Relevant academic research and scientific papers
[(PhBP3)Cu(PPh3)] as a surrogate of TpxCuL in homogeneous catalysis (PhBP3 = PhB(CH2PPh 2)3; Tpx = hydrotrispyrazolylborate)
Angeles Fuentes,Alvarez, Eleuterio,Caballero, Ana,Perez, Pedro J.
, p. 959 - 965 (2012)
The novel complexes [(PhBP3)Cu(L)] (PhBP3 = PhB(CH2PPh2)3, L = PPh3, 1; L = tetrahydrofuran, 2) have been synthesized and spectroscopically and, in the case of 1, structurally characterized. Both complexes undergo dissociation of the PPh3 or THF ligand in solution to deliver the (PhBP3)Cu unit, similar in geometry to and isoelectronic with TpxCu (Tp x = trispyrazolylborate ligand). A complete study of the catalytic properties of 1 has shown that it can be considered as a surrogate of Tp xCu. The study includes (a) olefin cyclopropanation, cyclopropenation, aziridination, halocarbon addition, and radical polymerization, (b) X-H (X = O, N) functionalization by carbene insertion, and (c) furan conversion into dihydropyridines. Since the observed activity is quite comparable to that already described for TpxCu complexes, this new catalytic system could become an alternative to the latter.
Selective synthesis of N-substituted 1,2-dihydropyridines from furans by copper-induced concurrent tandem catalysis
Fructos, Manuel R.,Alvarez, Eleuterio,Diaz-Requejo, M. Mar,Perez, Pedro J.
experimental part, p. 4600 - 4607 (2010/06/17)
A novel transformation in which mono- or dialkyl-substituted furans are converted into 1,2-dihydropyridines upon reaction with PhI - NTs at room temperature is reported. The reaction is catalyzed by complexes of general formula TpxM (M = Cu, Ag) and consists of a one-pot procedure with four consecutive catalytic cycles. Furan aziridination is followed by aziridine ring-opening, transimination reaction, inverse-electronic-demand aza-Diels-Alder reaction, and a final hydrogen elimination reaction. The mechanism of the overall transformation is proposed where the metal complex displays a crucial role along the reaction pathway.
