1217271-88-9Relevant academic research and scientific papers
One pot 'click' reactions: Tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition
Campbell-Verduyn, Lachlan S.,Szymanski, Wiktor,Postema, Christiaan P.,Dierckx, Rudi A.,Elsinga, Philip H.,Janssen, Dick B.,Feringa, Ben L.
, p. 898 - 900 (2010)
Halohydrin dehalogenase (HheC) can perform enantioselective azidolysis of aromatic epoxides to 1,2-azido alcohols which are subsequently ligated to alkynes producing chiral hydroxy triazoles in a one-pot procedure with excellent enantiomeric excess. The Royal Society of Chemistry 2010.
