1217343-52-6

Basic information

• Product Name: Y₈₆
• Synonyms: Y₈₆
• CAS NO: 1217343-52-6
• Molecular Weight: 1186.6
• Mol File: 1217343-52-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Y₈₆(CAS DataBase Reference)
• NIST Chemistry Reference: Y₈₆(1217343-52-6)
• EPA Substance Registry System: Y₈₆(1217343-52-6)

Safety Data

• Hazardous Substances Data: 1217343-52-6(Hazardous Substances Data)

Upstream product

• 331810-10-7 31-(trimethylsilylether)rapamycin 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 53123-88-9 sirolimus 
• 28863-62-9 (3,3-dimethyl-2,4-dioxacyclopentyl)methyl chloroformate 
• 143030-02-8 C₄₀-TBS-rap 

Downstream Products

• 1217343-53-7 Y₃₁-1 

Relevant articles and documents

Rapamycin Carbonic Ester Analogues, Pharmaceutical Compositions, Preparations and Uses Thereof

Rapalogs of formula I, pharmaceutically acceptable salts, pharmaceutical compositions, and preparation methods and uses thereof. The rapalogs have the structure of formula I and can be used as an anti-tumor medicament. Comparing with rapamycin, the rapalogs of the present invention exhibit enhanced water solubility, and improved pharmacological and pharmacokinetic properties by introducing a hydrophilic and polar group such as a hydroxyl.