1217436-70-8

Basic information

• Product Name: ethyl 4-phenylquinoline-6-carboxylate
• Synonyms: ethyl 4-phenylquinoline-6-carboxylate
• CAS NO: 1217436-70-8
• Molecular Weight: 277.323
• Mol File: 1217436-70-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-phenylquinoline-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-phenylquinoline-6-carboxylate(1217436-70-8)
• EPA Substance Registry System: ethyl 4-phenylquinoline-6-carboxylate(1217436-70-8)

Safety Data

• Hazardous Substances Data: 1217436-70-8(Hazardous Substances Data)

Upstream product

• 848738-27-2 ethyl 4-[(3-phenylprop-2-ynyl)amino]benzoate 

Relevant articles and documents

Synthesis of substituted quinolines by the electrophilic cyclization of n-(2-alkynyl)anilines

A wide variety of substituted quinolines are readily synthesized under mild reaction conditions by the 6-endo-dig electrophilic cyclization of N-(2-alkynyl)anilines by ICl, I2, Br2, PhSeBr, and p-O2NC6H4SCl. The reaction affords 3-halogen-, selenium- and sulfur-containing quinolines in moderate to good yields in the presence of various functional groups. Analogous quinolines bearing a hydrogen in the 3-position have been synthesized by the Hg(OTf)2-catalyzed ring closure of these same alkynylanilines.