1217526-89-0

Basic information

• Product Name: C₃₀H₄₂N₂
• Synonyms: C₃₀H₄₂N₂
• CAS NO: 1217526-89-0
• Molecular Weight: 430.677
• Mol File: 1217526-89-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₃₀H₄₂N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₀H₄₂N₂(1217526-89-0)
• EPA Substance Registry System: C₃₀H₄₂N₂(1217526-89-0)

Safety Data

• Hazardous Substances Data: 1217526-89-0(Hazardous Substances Data)

Upstream product

• 2579-20-6 cis, trans-1,3-dimethylaminocyclohexane 
• 1200-14-2 4-(n-butyl)benzaldehyde 

Downstream Products

• 1217600-20-8 (4-n-butylbenzyl)-(3-[4-n-butylbenzylaminomethyl]cyclohexylmethyl)amine 

Relevant articles and documents

Antimycobacterial activity evaluation, time-kill kinetic and 3D-QSAR study of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives

A series of C-(3-aminomethyl-cyclohexyl)-methylamine derivatives were synthesized and evaluated for their antitubercular activity. Some of the compounds exhibited potent activity against Mycobacterium tuberculosis H37Rv. One of the compound having t-butyl at para position of the benzene ring showed excellent activity even better than the standard drug ethambutol with MIC value 1.1 ± 0.2 μM. The time-kill kinetics study of two most active compounds showed rapid killing of the M. tuberculosis within 4 days. Additionally atom-based quantitative structure-activity relationship (QSAR) model was developed that gave a statistically satisfying result (R2) = 0.92, Q2 = 0.75, Pearson-R = 0.96 and effectively predicts the anti-tuberculosis activity of training and test set compounds.