1217604-63-1

Basic information

• Product Name: (R)-(1-MERCAPTOMETHYL-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (R)-2-BENZYL-2-N-BOCAMINO-ETHYL THIOL;(R)-(1-MERCAPTOMETHYL-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER
• CAS NO: 1217604-63-1
• Molecular Formula: C14H21NO2S
• Molecular Weight: 267.39
• Mol File: 1217604-63-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-(1-MERCAPTOMETHYL-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(1-MERCAPTOMETHYL-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER(1217604-63-1)
• EPA Substance Registry System: (R)-(1-MERCAPTOMETHYL-2-PHENYL-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER(1217604-63-1)

Safety Data

• Hazardous Substances Data: 1217604-63-1(Hazardous Substances Data)

Usage

General Description

The chemical "(R)-(1-mercaptomethyl-2-phenyl-ethyl)-carbamic acid tert-butyl ester" is a compound with a molecular formula C15H23NO2S. It is an ester of carbamic acid and is commonly known as a tert-butyl ester. This chemical is commonly used as a reagent in organic synthesis and pharmaceutical research. It is a chiral compound, meaning it has a non-superimposable mirror image, and this property makes it useful in asymmetric synthesis. The compound is also known for its potential use as an inhibitor in enzyme catalysis. Overall, this chemical has several potential applications in the fields of organic chemistry and pharmaceutical research.

Upstream product

• 3182-95-4 L-Phenylalaninol 
• 3385-94-2 hexamethyldisilathiane 
• 153782-96-8 (S)-N-t-butoxycarbonyl-2-phenylmethyl aziridine 
• 154669-56-4 (2S)-2-[N-(tert-butoxycarbonyl)amino]-1-iodo-3-phenylpropane 
• 141403-49-8 (2S)-2-[N-(tert-butoxycarbonyl)amino]-3-phenyl-O-(4-methylphenylsulfonyl)propan-1-ol 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 122818-32-0 (S)-2-<(tert-Butoxycarbonyl)amino>-3-phenylpropyl thioacetate 

Downstream Products

• 937207-74-4 C₂₅H₃₉N₃O₅S₃ 
• 141437-93-6 N-<2-<<<3-<<(2-amino-3-phenylpropyl)thio>carbonyl>propanoyl>thio>methyl>-3-phenylpropanoyl>glycine benzyl ester 
• 135949-89-2 [2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propyldisulfanylmethyl)-3-phenyl-propionylamino]-acetic acid benzyl ester 
• 135949-57-4 [2-((S)-2-Amino-3-phenyl-propyldisulfanylmethyl)-3-phenyl-propionylamino]-acetic acid benzyl ester 
• 141437-90-3 N-<2-<(acetylthio)methyl>-3-phenylpropanoyl>glycine S-(2-amino-3-phenylpropyl) thioester 

Relevant articles and documents

Mild and selective silicon-mediated access to enantioenriched 1,2-mercaptoamines and β-amino arylchalcogenides

Metal-free ring opening reactions of activated and unactivated aziridines with different silyl chalcogenides are described. Judicious tuning of the reaction conditions enables the synthesis of chiral enantioenriched N-Ts and N-Boc 1,2-mercaptoamines in good yields from the corresponding aziridines and bis(trimethylsilyl)sulfide. N-Protected and N-H unactivated aziridines are efficiently converted into the corresponding β-arylchalcogeno amines upon treatment with suitable arylchalcogenosilanes. The silicon-mediated ring opening reactions proceed with excellent regioselectivity and stereospecificity, allowing to access a wide array of synthetically and biologically valuable enantioenriched chalcogenoamines.

Potent and systemically active aminopeptidase N inhibitors designed from active-site investigation

Derivatives of amino acids bearing various zinc-coordinating moieties (SH, COOH, CONHOH, and PO3H2) were synthesized and tested for their ability to inhibit aminopeptidase N (APN). Among them, β-amino thiols were found to be the most