121766-24-3

Upstream product

• 121766-21-0 1-(4-Bromo-phenyl)-3-hydroxy-4-p-tolyl-azetidin-2-one 
• 94612-25-6 13g 
• 94612-47-2 N-(4-methylbenzyl)-4-bromoaniline 
• 94612-25-6 1-(4-Bromo-phenyl)-3-phenylsulfanyl-4-p-tolyl-azetidin-2-one 
• 94612-47-2 (4-Bromo-phenyl)-[1-p-tolyl-meth-(Z)-ylidene]-amine 
• 94612-32-5 1-(4-Bromo-phenyl)-3-chloro-3-phenylsulfanyl-4-p-tolyl-azetidin-2-one 
• 94612-32-5 (3R,4R)-1-(4-Bromo-phenyl)-3-chloro-3-phenylsulfanyl-4-p-tolyl-azetidin-2-one 

Downstream Products

• 121766-28-7 3-(4-Bromo-phenyl)-4-p-tolyl-oxazolidine-2,5-dione 
• 121766-32-3 (4-Bromo-phenylamino)-p-tolyl-acetic acid methyl ester 
• 136019-59-5 4-(4-Bromo-phenylamino)-3-oxo-4-p-tolyl-butyric acid methyl ester 

Relevant academic research and scientific papers

A β-Lactam Approach to γ-Amino-β-Keto Acid Derivatives.

Formation of γ-amino-β-keto acid derivatives by enolate acylation with N-carboxyanhydrides previously formed from α-keto β-lactams is described.

SYNTHETIC UTILITY OF AZETIDINE-2,3-DIONES: A NEW APPROACH TO 3-HYDROXYETHYL-β-LACTAMS AND α-AMINOACID DERIVATIVES

Baeyer-Villiger oxidation of azetidine-2,3-diones provides a new route to α-aminoacid-N-carboxyanhydrides.Conversion of azetidine-2,3-diones into 3-acetyl-β-lactams is also described.

A CONVENIENT SYNTHESIS OF AZETIDINE-2,3-DIONES (α-Keto-β-Lactams)

Azetidine-2,3-diones can be conveniently synthesized by mild hydrolisis of the product of the reaction between α-phenylthio-β-lactams and sulfuryl chloride.