1217898-67-3Relevant academic research and scientific papers
Diastereoselective addition of anisoles to: N-tert -butanesulfinyl imines via four-membered lithium cycles
Reddy, Leleti Rajender,Kotturi, Sharadsrikar,Waman, Yogesh,Patel, Chirag,Patwa, Aditya,Shenoy, Rajesh
, p. 7007 - 7009 (2018)
A highly regio- and diastereo-selective ortho-lithiation/addition of anisoles to N-tert-butanesulfinyl imines resulting in the selective formation of chiral α-branched amines is described. This method is also efficient for highly regioselective benzylic lithiation of o-methylanisoles, followed by diastereoselective addition to N-tert-butanesulfinyl imines.
AN IMPROVED ASYMMETRIC SYNTHESIS OF ALPHA-BRANCHED CHIRAL AMINES
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Page/Page column 18; 19, (2019/11/12)
The present invention relates to an improved asymmetric synthesis of alpha- branched amines (hereafter referred to as the compound (1)) and relative chiral amines (1'') or its pharmaceutically acceptable salt and derivatives. The process comprises an unus
