1217899-52-9Relevant academic research and scientific papers
PROCESS FOR THE SYNTHESIS OF DEUTERATED CAPSAICIN, CAPSAICINOIDS AND SYNTHETIC CAPSAICIN ANALOGS
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, (2021/01/29)
The present application provides novel processes for the synthesis of deuterated intermediates of capsaicinoids, particularly II, III, IV and V of capsaicinoids, relating to pharmaceutical applications. The invention also provides novel intermediates of compounds of formula IX, XIV, XV, XVI, XVII, XVIII, XX and XXI utilized in the process of making deuterated capsaicin II, III, IV and V.
Synthesis and elucidation of deuterated vanillylamine hydrochloride and capsaicin
Kim, Sang Wook,Park, Jeong Hoon,Jung, Soon Jae,Choi, Tae Bum,Hur, Min Goo,Yang, Seung Dae,Yu, Kook Hyun
experimental part, p. 563 - 565 (2010/07/02)
Capsaicin is the major pungent component of hot peppers, which belong to the plant genus Capsicum. Although the biosynthesis of capsaicin is known to involve the condensation of vanillylamine and 8-methylnonenoic acid by capsaicin synthase, the mechanism of biosynthesis is still not fully understood. In this study, deuterium labelled versions of capsaicin and the precursor vanillylamine were synthesized in order to investigate the biosynthesis of capsaicin in hot peppers. Copyright
