121862-35-9Relevant academic research and scientific papers
Chemistry of ketone α,β-dianions. Acylation reactions of dianion cuprates by acid chlorides
Ryu, Ilhyong,Ikebe, Masanobu,Sonoda, Noboru,Yamato, Shin-Ya,Yamamura, Go-Hei,Komatsu, Mitsuo
, p. 1257 - 1259 (2002)
The cross-coupling reaction of dianion cuprates, generated from ketone α,β-dianions and copper salts, with acid chlorides, was studied. The reaction gave good to moderate yields of unsymmetrical 1,4-diketones. The consecutive treatment of a dianion cuprate with cyclohexanecarbonyl chloride and methyl iodide or two different acid chlorides gave 2-methyl-substituted 1,4-diketone or triketone, respectively.
DIVERGENT SYNTHESIS OF 1,3- AND 1,4-DIKETONES FROM β-METHOXY-γ-PHENYLTHIO KETONES ACCESSIBLE THROUGH NOVEL PHENYLTHIO MIGRATION REACTION
Sato, Tsuneo,Inoue, Masami,Kobara, Satoru,Otera, Junzo,Nozaki, Hitosi
, p. 91 - 94 (2007/10/02)
Both 1,3- and 1.4-diketones are obtained from common precursors, β-methoxy-γ-phenylthio ketones.These compounds are derived through the novel phenylthio migration reaction of the aldehyde adducts with methoxy(phenylthio)-methane upon exposure to enol silyl ethers.The compounds thus obtained are converted into 1,3- and 1,4-diketones.
