1218786-38-9Relevant academic research and scientific papers
Rearrangement strategy for the synthesis of 2-aminoanilines
Porzelle, Achim,Woodrow, Michael D.,Tomkinson, Nicholas C.O.
supporting information; experimental part, p. 1492 - 1495 (2010/07/03)
(Figure Presented) Treatment of N-aryl hydroxylamines with trichloroacetonitrile in the presence of imidazole provides a simple and effective method for the preparation of synthetically versatile 2-aminoanilines. Reactions proceed in DMF at 40°C, providing the products In up to 86% isolated yield.
