1218786-89-0

Upstream product

• 1246467-04-8 ethyl [2-oxo-3-(4-chlorophenyl)-2H-[1,8]-naphthyridin-1-yl]acetate 
• 439277-54-0 1,2-dihydro-3-(4-chlorophenyl)-2H-[1,8]-naphthyridin-2-one 

Downstream Products

• 1218786-93-6 C₂₄H₁₈Cl₂N₄O₂ 
• 1218786-94-7 C₂₄H₁₈BrClN₄O₂ 
• 1218786-90-3 C₂₄H₁₉ClN₄O₂ 
• 1218786-91-4 C₂₅H₂₁ClN₄O₂ 
• 1218786-96-9 C₂₄H₁₈ClN₅O₄ 
• 1218786-92-5 C₂₅H₂₁ClN₄O₃ 
• 1218786-95-8 C₂₄H₁₈ClN₅O₄ 
• 1218786-97-0 C₂₈H₂₁ClN₄O₂ 
• 1246467-17-3 C₂₃H₁₅ClN₄O₂ 
• 1246467-18-4 C₂₄H₁₇ClN₄O₂ 
• 1246467-19-5 C₂₄H₁₇ClN₄O₃ 
• 1246467-20-8 C₂₃H₁₄Cl₂N₄O₂ 
• 1246467-21-9 C₂₃H₁₄Cl₂N₄O₂ 
• 1246467-22-0 C₂₃H₁₃Cl₃N₄O₂ 

Relevant academic research and scientific papers

Hypervalent iodine mediated synthesis of 1,3,4-oxadiazolyl-1,8- naphthyridines under solvent-free microwave irradiation

An efficient and convenient protocol for the synthesis of 1 -(5-aryl-[1,3,4] oxadiazol-2-ylmethyl)-3-(p-chlorophenyl)-1 H-[1,8]- naphthyridin-2-ones 5 from [2-oxo-3-(p-chlorophenyl)-2/-/-[1,8] naphthyridin-1-yl] acetic acid arylidenehydrazides 4 using iodobenzene diacetate (IBD) under solvent-free microwave irradiation is described. The products are obtained in good yields and in the state of high purity. The structures of the compounds 2-5 have been established on the basis of spectral (IR, 1H NMR and MS) and analytical data.

Microwave assisted synthesis of 1,3,4-oxadiazolyl 1, 8-naphthyridines under solvent-free conditions using solid support

A convient synthesis of 1-(4-acetyl-5-aryl-5-methyl-[1,3, 4]oxadiazol-2-ylmethyl)-3-(4-chlorophenyl)-1H-[1, 8]naphthyridin-2-ones, by cyclization of acetophenone [2-oxo-3-(4-chlorophenyl)-2H-[1,8]-naphthyridin-1 -yl]methylcarbonylhydrazones with acetic anhydride using silica gel as solid support under microwave irradition is described. The structural assignments of the compounds are based on their elemental analyses and spectral data.