1218787-39-3

Upstream product

• 55456-40-1 benzyl 2-aminoisobutyrate 

Downstream Products

• 1218787-65-5 1-[1-(benzyloxycarbonyl)isopropyl]-1'-(4-cyanophenyl)-1H,1'H-4,4'-bis(1,2,3-triazole) 
• 1218787-50-8 1-[1-(benzyloxycarbonyl)-isopropyl]-4-ethynyl-1H-1,2,3-triazole 
• 1218787-55-3 C₂₆H₂₈N₆O₄ 
• 1218787-42-8 1-[1-(benzyloxycarbonyl)isopropyl]-4-hydroxymethyl-1H-1,2,3-triazole 
• 1433554-91-6 1-[2-(benzyloxycarbonyl)-2-propyl]-4-[3-(trimethylsilyl)prop-2-ynyl]-1H-1,3,3-triazole 
• 1433554-94-9 1-[2-(benzyloxycarbonyl)-2-propyl]-4-propargyl-1H-1,2,3-triazole 
• 1433555-00-0 1-[2-(benzyloxycarbonyl)-2-propyl]-1'-(2,3,4,6-tetra-O-acetyl-α-D-mannosyl)-4,4'-methylenebis(1H-1,2,3-triazole) 
• 1433555-02-2 1-[2-(benzyloxycarbonyl)-2-propyl]-1'-(2,3,4-tri-O-acetyl-β-L-fucosyl)-4,4'-methylenebis(1H-1,2,3-triazole) 

Relevant academic research and scientific papers

Modulating lectin inhibition with N-glycosyl-1,2,3-triazole scaffolds

The synthesis of three families of sialyl LewisX (sLe X) mimetics based on triazole and bis-triazole scaffolds is reported. The flexibility of these mimetics is dictated by the scaffold and gradually increases from flexible to rigid.

"click" synthesis of nonsymmetrical bis(1,2,3-triazoles)

Chemical Fig. Repretation Unsymmetrically 1,1'-disubstituted 4,4'-bis-1 H-1,2,3-triazoles 4 have been prepared from 4-ethynyl-1,2,3-triazoles 5 and azides. Following a "double-click" strategy, two complementary approaches were implemented for the preparation of the key 4-ethynyltriazole Intermediates 5: (a) the stepwise Swern oxidatlon/Ohira-Bestman alkynylation of readily available 4-hydroxymethyl-1,2,3-triazoles 8 and (b) the stepwise cycloaddition of TMS-1,4-butadiyne 9. The method is highlighted by Its compatibility with orthogonally protected and functlonallzed saccharide-peptide hybrids and its ability to be extended to the trlsubstituted counterparts 12.