1218811-72-3

Basic information

• Product Name: 2-(4-chlorophenyl)-5-[(4-methylphenyl)ethynyl]-1,3,4-oxadiazole
• Synonyms: 2-(4-chlorophenyl)-5-[(4-methylphenyl)ethynyl]-1,3,4-oxadiazole
• CAS NO: 1218811-72-3
• Molecular Weight: 294.74
• Mol File: 1218811-72-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-5-[(4-methylphenyl)ethynyl]-1,3,4-oxadiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-5-[(4-methylphenyl)ethynyl]-1,3,4-oxadiazole(1218811-72-3)
• EPA Substance Registry System: 2-(4-chlorophenyl)-5-[(4-methylphenyl)ethynyl]-1,3,4-oxadiazole(1218811-72-3)

Safety Data

• Hazardous Substances Data: 1218811-72-3(Hazardous Substances Data)

Upstream product

• 23289-10-3 2-(4-chlorophenyl)-1,3,4-oxadiazole 
• 766-97-2 4-n-methylphenylacetylene 
• 31638-66-1 (p-tolylethynyl)copper 

Relevant articles and documents

Room-temperature direct alkynylation of arenes with copper acetylides

C-H bond in azoles and polyhalogenated arenes can be smoothly activated by copper acetylides to give the corresponding alkynylated (hetero)arenes by simple reaction at room temperature in the presence of phenanthroline and lithium tert-butoxide under an oxygen atmosphere. These stable, unreactive, and readily available polymers act as especially efficient and practical reagents for the introduction of an alkyne group to a wide number of arenes under remarkably mild conditions.