1218999-89-3Relevant articles and documents
Phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: Evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity
Yu, Gang,Chowdhury, Morshed A.,Abdellatif, Khaled R.A.,Dong, Ying,Praveen Rao,Das, Dipankar,Velazquez, Carlos A.,Suresh, Mavanur R.,Knaus, Edward E.
, p. 896 - 902 (2010)
A novel class of phenylacetic acid regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore attached to its C-2, C-3 or C-4 position was designed for evaluation as anti-inflammatory (AI) agents. A number of compounds exhibited a com