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Usage

Uses

Used in Asymmetric Catalysis:
DCPPE is utilized as a ligand in asymmetric catalysis, particularly for facilitating asymmetric hydrogenation reactions and other catalytic processes. Its unique steric and electronic properties make it a valuable tool in enhancing the selectivity and efficiency of these reactions.
Used in Pharmaceutical Production:
In the pharmaceutical industry, DCPPE is employed as a crucial component in the synthesis of various drugs and fine chemicals. Its role in asymmetric catalysis aids in the production of enantiomerically pure compounds, which are essential for the development of effective and safe medications.
Used in Organic Synthesis:
DCPPE is also used in organic synthesis as a ligand to improve the yield and selectivity of specific reactions. Its application in this field contributes to the development of novel compounds and materials with potential applications in various industries.

Upstream product

• 75421-30-6 (S)-cyclohexyl-1,2-bis(p-toluenesulfonyloxy)ethane 
• 65567-06-8 lithium diphenylphosphide 

Relevant academic research and scientific papers

1,2-Bis(diphenylphosphino)-1-cyclohexylethane. A New Chiral Phosphine Ligand for Catalytic Chiral Hydrogenations

The new chiral bidentate phosphine ligand (R)-1,2-bis(diphenylphosphino)-1-cyclohexylethane ((R)-Cycphos) has been prepared.The rhodium(I) cationic complex of this phosphine serves as an effective homogeneous asymmetric hydrogenation catalyst for the reduction of (Z)-α-amidoacrylic acids at ambient temperature and pressure.Optical yields for the corresponding (S)-α-amino acid derivatives that are produced are generally above 90percent.The success of this ligand in giving higher optical yields than those obtained from other structurally analogous phosphines is rationalized in terms of the bulky cyclohexyl substituent affording a more stereochemically rigid chelating phosphine.

Process for producing optically active benzhydrol compounds

A process for producing a benzhydrol compound (II) which comprises hydrogenating a benzophenone compound (I) in the presence of a hydrogenation catalyst consisting of a transition metal complex, a base and an optically active diamine compound: STR1 wherein R1 to R10 each represents H, OH, C1-4 alkyl, C1-4 alkoxy, C1-4 alkanoyl, etc., R2 and R3, and R8 and R9 may form --CH=CH--CH=CH--, or any two of R1 to R9 adjacent to each other may be bonded to thereby form --OCH2 O-- or --(CH2)3 --. By using this process, optically active benzhydrol compounds which have a high purity and are useful as, for example, intermediates in the synthesis of drugs can be produced by simple procedures.