(R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE

Base Information

• Chemical Name: (R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE
• CAS No.: 121902-84-9
• Molecular Formula: C₃₂H₃₄P₂
• Molecular Weight: 480.569
• Mol file: 121902-84-9.mol

Synonyms:(R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE

Chemical Property of (R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE

Chemical Property:

• PSA: 27.18000
• LogP: 7.34360

Purity/Quality:

99%min ^*data from raw suppliers

(R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE

There total 2 articles about (R)-1,2-BIS(DIPHENYLPHOSPHINO)CYCLOHEXYLETHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-cyclohexyl-1,2-bis(p-toluenesulfonyloxy)ethane (75421-30-6) + lithium diphenylphosphide (65567-06-8,4541-02-0) → (R)-1,2-bis(diphenylphosphino)cyclohexylethane (75421-31-7,121902-84-9)

Guidance literature:

Yield given. Multistep reaction;

DOI:10.1021/jo01313a033

Reference yield:

→ (R)-1,2-bis-(diphenylphosphino)-1-cyclohexylethane (121902-84-9)

Guidance literature:

Reference yield: 21.0%

chloro(cyclopentadienyl)bis(triphenylphosphine)ruthenium (II) (32993-05-8) + (R)-1,2-bis(diphenylphosphino)cyclohexylethane (75421-31-7,121902-84-9) → [(S)-1-cyclohexyl-1,2-bis(diphenylphosphino)ethane-PP']chloro(η5-cyclopentadienyl)(R)ruthenium + [(S)-1-cyclohexyl-1,2-bis(diphenylphosphino)ethane-PP']chloro(η5-cyclopentadienyl)(S)ruthenium

Guidance literature:

In toluene; soln. of Ru-complex and ligand (molar ratio 1:1.05) in toluene was refluxed for 6 h, cooled; volume reduced, n-hexane added, ppt. filtered, washed with n-hexane, dissolved in benzene, n-hexane added, stood at room temp. ((S)Ru-isomer),crystd. from mother liquor at -20°C ((R)Ru-isomer); elem. anal.;

DOI:10.1039/DT9830002293

upstream raw materials:

(S)-cyclohexyl-1,2-bis(p-toluenesulfonyloxy)ethane

lithium diphenylphosphide

Refernces

• 1、 -. "Process for producing optically active benzhydrol compounds". . . Retrieved 2008/06/13.