1219467-74-9Relevant articles and documents
Asymmetric intramolecular oxa-Michael reactions of cyclohexadienones catalyzed by a primary amine salt
Wu, Wenbin,Li, Xin,Huang, Huicai,Yuan, Xiaoqian,Lu, Junzhu,Zhu, Kailong,Ye, Jinxing
supporting information, p. 1743 - 1747 (2013/04/10)
Michael brings the rings: An asymmetric intramolecular oxa-Michael reaction involving iminium activation has been developed. This reaction provides enantioenriched 1,4-dioxane derivatives with up to 99 % yield and 98 % ee. The method allows for concise and stereoselective access to stereodiverse, complex tetracyclic compounds containing a bicyclo[2.2.2]octan-2-one backbone with multiple chiral centers. Copyright
