1219467-85-2Relevant academic research and scientific papers
Asymmetric intramolecular oxa-Michael reactions of cyclohexadienones catalyzed by a primary amine salt
Wu, Wenbin,Li, Xin,Huang, Huicai,Yuan, Xiaoqian,Lu, Junzhu,Zhu, Kailong,Ye, Jinxing
, p. 1743 - 1747 (2013/04/10)
Michael brings the rings: An asymmetric intramolecular oxa-Michael reaction involving iminium activation has been developed. This reaction provides enantioenriched 1,4-dioxane derivatives with up to 99 % yield and 98 % ee. The method allows for concise and stereoselective access to stereodiverse, complex tetracyclic compounds containing a bicyclo[2.2.2]octan-2-one backbone with multiple chiral centers. Copyright
Desymmetrization of cyclohexadienones via bronsted acid-catalyzed enantioselective oxo-michael reaction
Gu, Qing,Rong, Zi-Qiang,Zheng, Chao,You, Shu-Li
supporting information; experimental part, p. 4056 - 4057 (2010/05/01)
Chemical Reaction Reprentation Desymmetrlzatlon of cyclohexadlenones via enantloselectlve oxo-Mlchael reaction catalyzed by chlral phosphoric add to afford highly enantloenrlched 1,4-dloxane and tetrahydrofuran derivatives In excellent yields has been realized. The newly established methodology allows the facile enantloselectlve synthesis of clerolndlclns C, D, and F.Copyright
