1219707-39-7 Usage
Description
Delpazolid is an oxazolidinone antibiotic that demonstrates potent activity against a broad spectrum of Gram-positive bacterial clinical isolates. It is particularly effective against resistant strains, such as methicillin-resistant S. aureus (MRSA), methicillin-resistant coagulase-negative staphylococci (MRCNS), and penicillin-resistant S. pneumoniae. Delpazolid has shown to enhance survival rates in mouse models of systemic infections caused by MRSA, E. faecalis, S. pneumoniae, and H. influenzae.
Uses
Used in Pharmaceutical Industry:
Delpazolid is used as an antibiotic for treating various Gram-positive bacterial infections, particularly those caused by resistant strains. Its effectiveness against MRSA, MRCNS, and penicillin-resistant S. pneumoniae makes it a valuable addition to the arsenal of antibiotics used to combat drug-resistant infections.
Used in Clinical Settings:
In clinical settings, delpazolid is utilized to improve patient outcomes by targeting resistant bacterial strains that are difficult to treat with conventional antibiotics. Its ability to increase survival rates in mouse models of systemic infections highlights its potential as a life-saving treatment option for severe bacterial infections in humans.
Used in Research and Development:
Delpazolid is also used in the research and development of new antibiotics and treatment strategies for drug-resistant bacterial infections. Its unique mechanism of action and effectiveness against a wide range of Gram-positive bacteria make it an important compound for further study and potential development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1219707-39-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,9,7,0 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1219707-39:
(9*1)+(8*2)+(7*1)+(6*9)+(5*7)+(4*0)+(3*7)+(2*3)+(1*9)=157
157 % 10 = 7
So 1219707-39-7 is a valid CAS Registry Number.
1219707-39-7Relevant articles and documents
METHOD FOR PREPARING (R)-3-(3-FLUORO-4-(1-METHYL-5,6-DIHYDRO-1,2,4-TRIAZIN-4(1H)-YL)PHENYL)-5-(SUBSTITUTED METHYL)OXAZOLIDIN-2-ONE DERIVATIVES
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, (2013/02/28)
Provided are a method for preparing (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are oxazolidinone antibiotic compounds having a cyclic amidrazone group, represented by Chemical Formula 1, and intermediates thereof, and uses 3,4-difluoro-4-nitrobenzen as a starting material. According to the preparation method of the present invention, (R)-3-(3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl)-5-(substituted methyl)oxazolidin-2-one derivatives, which are useful as oxazolidinone antibiotics, can be prepared in high purity and high yield in a simpler manner than conventional methods.
