121998-08-1 Usage
Naturally occurring
1'-O-acetylpaxilline is found in certain types of fungi.
Indole alkaloid
It belongs to a class of chemical compounds that includes many alkaloids found in nature.
Derived from paxilline
It is a modified version of the parent compound paxilline.
Potent tremorgenic effects
It causes muscle tremors and other involuntary movements.
Selective blocker of voltage-gated potassium channels
It specifically targets and blocks these channels in neurons, leading to hyperexcitability and tremors.
Potential pharmacological effects
It has been studied for its ability to inhibit the growth of certain cancer cells and for its potential in treating conditions such as epilepsy and movement disorders.
Diverse biological activities
1'-O-acetylpaxilline has a range of biological activities and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 121998-08-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,1,9,9 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 121998-08:
(8*1)+(7*2)+(6*1)+(5*9)+(4*9)+(3*8)+(2*0)+(1*8)=141
141 % 10 = 1
So 121998-08-1 is a valid CAS Registry Number.
121998-08-1Relevant articles and documents
Isolation of a new tremorgenic indoloditerpene, 1'-O-acetylpaxilline, from Emericella striata and distribution of paxilline in Emericella spp.
Nozawa,Horie,Udagawa,Kawai,Yamazaki
, p. 1387 - 1389 (1989)
The distribution of a tremorgenic mycotoxin, paxilline (1), was investigated in 19 species belonging to the genus Emericella. It was found that Emericella desertorum, E. foveolata, and E. striata produced paxilline (1). A new type of indoloditerpene, emindole DA (4), was also found in E. quadrilineata. A new tremorgenic indoloditerpene, 1'-O-acetylpaxilline (3), was isolated from the mycelium of E. striata. Its structure was established on the basis of spectroscopic investigations.
