Isolation of a new tremorgenic indoloditerpene, 1'-O-acetylpaxilline, from Emericella striata and distribution of paxilline in Emericella spp.

DOI: 10.1248/cpb.37.1387

Source and publish data:

Chemical and pharmaceutical bulletin p. 1387 - 1389 (1989)

Update date:2022-08-04

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Authors:

Nozawa Nozawa

Horie Horie

Udagawa Udagawa

Kawai Kawai

Yamazaki

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Article abstract of DOI:10.1248/cpb.37.1387

The distribution of a tremorgenic mycotoxin, paxilline (1), was investigated in 19 species belonging to the genus Emericella. It was found that Emericella desertorum, E. foveolata, and E. striata produced paxilline (1). A new type of indoloditerpene, emindole DA (4), was also found in E. quadrilineata. A new tremorgenic indoloditerpene, 1'-O-acetylpaxilline (3), was isolated from the mycelium of E. striata. Its structure was established on the basis of spectroscopic investigations.

Full text of DOI:10.1248/cpb.37.1387

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