1220100-53-7Relevant academic research and scientific papers
Dibenzothiophenesulfilimines: A Convenient Approach to Intermolecular Rhodium-Catalysed C?H Amidation
Antoni, Patrick W.,Mackenroth, Alexandra V.,Mulks, Florian F.,Rudolph, Matthias,Helmchen, Günter,Hashmi, A. Stephen K.
supporting information, p. 8235 - 8238 (2020/06/17)
A sulfilimine-based Group 9 transition-metal-catalysed C?H amidation procedure is reported. Dibenzothiophene-based sulfilimines were shown to constitute a class of novel amidation reagents which enable the transfer of a wide range of N-sulfonyl and N-acyl
Chelation-Assisted Rhodium-Catalyzed Direct Amidation with Amidobenziodoxolones: C(sp2)-H, C(sp3)-H, and Late-Stage Functionalizations
Hu, Xu-Hong,Yang, Xiao-Fei,Loh, Teck-Peng
, p. 5930 - 5934 (2016/09/09)
Air-stable and convenient amidobenziodoxolones as an amidating reagent were disclosed to enable direct amidation on a wide range of C(sp2)-H bonds of (hetero)arenes and alkenes, as well as unactivated C(sp3)-H bonds under RhIII catalysis. The approach to access 49 examples of structurally diverse amides is featured by mild conditions, complete chemoselectivity and regioselectivity, broad substrate scope (not limited to strongly heterocyclic coordinating groups), and tolerance of valuable functional substituents, such as unprotected amine and hydroxyl groups. The synthetic applicability of this protocol is also demonstrated by late-stage functionalization of biologically important scaffolds.
Rhodium(III)-catalyzed intermolecular N-chelator-directed aromatic C-H amidation with amides
Zhao, Huaiqing,Shang, Yaping,Su, Weiping
supporting information, p. 5106 - 5109 (2013/10/22)
Rh(III)-catalyzed intermolecular direct aromatic C-H bond amidation with amides has been accomplished under mild reaction conditions. This protocol is applicable to a broad range of N-chelator-containing arenes amidated with aromatic and aliphatic sulfonamides. A possible mechanism is proposed according to the experimental results.
Copper-catalyzed amidation of 2-phenylpyridine with oxygen as the terminal oxidant
John, Alex,Nicholas, Kenneth M.
experimental part, p. 4158 - 4162 (2011/07/30)
The Cu(OAc)2-catalyzed, O2-mediated amidation of 2-phenylpyridine via C-H bond activation is reported. A variety of nitrogen reagents including sulfonamides, carboxamides, and anilines participate in the reaction in moderate to good
Mechanism of C-F reductive elimination from palladium(IV) fluorides
Furuya, Takeru,Benitez, Diego,Tkatchouk, Ekaterina,Strom, Alexandra E.,Tang, Pingping,Goddard III, William A.,Ritter, Tobias
supporting information; experimental part, p. 3793 - 3807 (2010/05/15)
The first systematic mechanism study of C-F reductive elimination from a transition metal complex is described. C-F bond formation from three different Pd(IV) fluoride complexes was mechanistically evaluated. The experimental data suggest that reductive elimination occurs from cationic Pd(IV) fluoride complexes via a dissociative mechanism. The ancillary pyridyl-sulfonamide ligand plays a crucial role for C-F reductive elimination, likely due to a K 3 coordination mode, in which an oxygen atom of the sulfonyl group coordinates to Pd. The pyridyl-sulfonamide can support Pd(IV) and has the appropriate geometry and electronic structure to induce reductive elimination.
