29528-30-1

Usage

Uses

Used in Pharmaceutical Industry:
2-(2-PYRIDYL)ANILINE is used as an intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing medications.
Used in Dye Industry:
2-(2-PYRIDYL)ANILINE is used as a component in the production of dyes, enhancing the color properties and stability of these products.
Used in Organic Compounds Synthesis:
2-(2-PYRIDYL)ANILINE is used as a building block in the creation of various organic compounds, facilitating the synthesis of complex molecules for a wide range of applications.
Used as a Catalyst:
2-(2-PYRIDYL)ANILINE is used as a catalyst in chemical reactions, improving the efficiency and selectivity of these processes.
Environmental and Health Considerations:
2-(2-PYRIDYL)ANILINE is considered a hazardous chemical, and its potential as an environmental pollutant requires careful management to minimize health risks to humans and animals. Proper handling, storage, and disposal methods are crucial to ensure safety and environmental protection.

InChI:InChI=1/C11H10N2/c12-10-6-2-1-5-9(10)11-7-3-4-8-13-11/h1-8H,12H2

Upstream product

• 4253-81-0 2-(2-nitrophenyl)pyridine 
• 110-86-1 pyridine 
• 615-43-0 2-iodophenylamine 
• 609-73-4 o-nitroiodobenzene 
• 109-04-6 2-bromo-pyridine 
• 615-36-1 2-bromoaniline 
• 62681-29-2 2-(2-azidophenyl)pyridine 
• 1008-89-5 2-phenylpyridine 
• 1258862-62-2 2-(2-dibromoborylphenyl)pyridine 
• 197958-29-5 pyridin-2-ylboronic acid 
• 1607824-59-8 2-(2-(pyridin-2-yl)phenyl)benzo[d]isothiazol-3(2H)-one 1,1-dioxide 
• 5570-18-3 2-aminophenylboronic acid 
• 5570-19-4 2-nitrophenylboronic acid 
• 109-09-1 2-chloropyridine 

Downstream Products

• 62681-29-2 2-(2-azidophenyl)pyridine 
• 138622-17-0 ethyl (E)-2-<2-(pyridin-2'-yl)phenylhydrazono>propanoate 
• 97188-56-2 Dithiocarbonic acid O-ethyl ester S-(2-pyridin-2-yl-phenyl) ester 
• 97188-57-3 2-(2-pyridyl)thiophenol 
• 188679-91-6 bis[2-(2-pyridyl)phenyl] disulfide 
• 142672-91-1 2-(o-triphenylphosphoranilidenamino)phenylpyridine 
• 142754-44-7 6-Phenyl-pyrido[1,2-c]quinazolin-7-ylium; chloride 
• 142754-45-8 6-p-Tolyl-pyrido[1,2-c]quinazolin-7-ylium; chloride 
• 142754-46-9 6-(4-Fluoro-phenyl)-pyrido[1,2-c]quinazolin-7-ylium; chloride 
• 142754-47-0 6-(4-Methoxy-phenyl)-pyrido[1,2-c]quinazolin-7-ylium; chloride 
• 113623-88-4 1-(2-Pyridin-2-yl-phenylazo)-naphthalen-2-ol 
• 1040922-30-2 2-nitro-N-(2-(pyridin-2-yl)phenyl)benzenesulfonamide 
• 1220100-58-2 2-(2-pyridinyl)-4-tert-butylbenzenesulfonanilide 

Relevant academic research and scientific papers

Redox-Active Ligand Assisted Catalytic Water Oxidation by a RuIV=O Intermediate

Water splitting is one of the most promising solutions for storing solar energy in a chemical bond. Water oxidation is still the bottleneck step because of its inherent difficulty and the limited understanding of the O?O bond formation mechanism. Molecular catalysts provide a platform for understanding this process in depth and have received wide attention since the first Ru-based catalyst was reported in 1982. RuV=O is considered a key intermediate to initiate the O?O bond formation through either a water nucleophilic attack (WNA) pathway or a bimolecular coupling (I2M) pathway. Herein, we report a Ru-based catalyst that displays water oxidation reactivity with RuIV=(O) with the help of a redox-active ligand at pH 7.0. The results of electrochemical studies and DFT calculations disclose that ligand oxidation could significantly improve the reactivity of RuIV=O toward water oxidation. Under these conditions, sustained water oxidation catalysis occurs at reasonable rates with low overpotential (ca. 183 mV).

Facile formation of imidazolinium salt by reaction of corresponding diamine and trimethyl orthoformate in 1,1,1,3,3,3-hexafluoroisopropanol

The preparation of imidazolinium salts, which can be used as precursors of pincer-type N-heterocyclic carbene ligands, is described. The formation of imidazolinium salts under standard conditions is difficult, but they have been successfully synthesized by reaction of the corresponding diamines and trimethyl orthoformate in 1,1,1,3,3,3-hexafluoroisopropanol. The synthesis of new chiral C2 symmetric imidazolinium salts is also described.

Ruthenium-catalyzed: Ortho -selective CAr-H amination of heteroaryl arenes with di- tert -butyldiaziridinone

Application of an oxidative amination reagent (di-tert-butyldiaziridinone) to the Ru3(CO)12-catalyzed ortho-selective CAr-H amination reaction is described. This strategy shows good functional group compatibility with vari

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Signal transducers and activators of transcription 5A and 5B (STAT5A and STAT5B) are two closely related STAT family members that are crucial downstream effectors of tyrosine kinase oncoproteins such as FLT3-ITD in acute myeloid leukemia (AML) and BCR-ABL

COMPOUNDS AND METHODS FOR TREATING CANCER

Substituted cinnamamide compounds and analogs, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat, prevent or ameliorate cancer are provided.

Rhodium(III)-catalyzed chelation-assisted C-H imidation of arenes via umpolung of the imidating reagent

Rh(III)-catalyzed, chelation-assisted oxidative C?H imidation of arenes with N?H imide have been realized using PhI(OAc)2 as an oxidant. This transformation exhibits a broad substrate scope and tolerates various functional groups. The reaction proceeded via in situ generation of an iodine(III) imido. DFT calculations suggest that this oxidative imidaton system proceeds via a Rh(III)-Rh(V)-Rh(III) pathway.

Phenanthridine Derivatives and organic light-emitting diode including the same

PURPOSE: A phenanthridine derivative compound is provided to obatin an organic light emitting diode with excellent light emitting property. CONSTITUTION: A phenanthridine derivative compound is denoted by chemical formula 1 or 2. An organic light emitting diode contains an anode, a cathode, and the phenanthridine derivative compounds inserted between the anode and cathode. The organic light emitting diode further contains a hole injection layer, a hole transport layer, an electron blocking layer, a hole blocking layer, an electron transport layer, or an electron injection layer formed by monomer deposition or solution process.

Lewis Acid/Br?nsted Acid Controlled Pd(II)-Catalyzed Chemodivergent Functionalization of C(sp2)-H Bonds with N-(Arylthio)i(a)mides

An efficient and chemodivergent palladium-catalyzed thiolation (C-S) and imidation (C-N) of directing group-assisted C-H bonds have been accomplished employing N-(arylthio)imides in combination with either Br?nsted acid or Lewis acid, respectively. Notable features of the developed methodologies include excellent diversity, high functional group tolerance, wide substrate scope, and use of a single N-S reagent. Importantly, the developed hypothesis was also successfully extended to the amidation of C-H bonds. A plausible mechanistic pathway was proposed based on the preliminary mechanistic study.

Discovery of 2-(pyridin-2-yl)aniline as a directing group for the sp2 C-H bond amination mediated by cupric acetate

2-(Pyridin-2-yl) aniline was designed as a new, removable directing group in promoting C-H amination mediated by cupric acetate. Employing this auxiliary, the β-C(sp2)-H bonds of benzamide derivatives can be effectively aminated with a variety of amines in moderate to good yields with good functional group tolerance in air. In addition, the quinazolinone derivatives were isolated from the reaction mixture of N-(2-(pyridin-2-yl)phenyl)benzamide with formamide or 5-nitroindole. The corresponding mechanism is discussed. These results indicate that 2-(pyridine-2-yl)aniline can serve as a directing group.

Visible-light-induced regioselective synthesis of polyheteroaromatic compounds

A method for visible-light-induced synthesis of polyheteroaromatics from 2-heteroaryl-substituted anilines and heteroarylalkynes was developed. The process, which uses fac-Ir(ppy)3 as the photocatalyst and tBuONO as the diazotization reagent, is highly regioselective.