1220105-01-0Relevant articles and documents
Sequential perfluoroalkylation and asymmetric reduction of nitriles triggered with perfluoroalkyl titanates: catalytic asymmetric synthesis of perfluoroalkyl amines
Mikami, Koichi,Murase, Tatsushi,Zhai, Lili,Kawauchi, Susumu,Itoh, Yoshimitsu,Ito, Shigekazu
, p. 1371 - 1373 (2010)
Highly enantio-enriched perfluoroalkyl amines are shown to be synthesized by perfluoroalkylation and asymmetric reduction of nitriles. Perfluoroalkylation of nitriles can be attained by the Lewis acidic perfluoroalkyl titanate reagents to give acyclic ket