1220123-33-0

Basic information

• Product Name: N-((1S,3R)-3-(ethylamino)-2,2,3-trimethylcyclopentyl)benzamide
• Synonyms: N-((1S,3R)-3-(ethylamino)-2,2,3-trimethylcyclopentyl)benzamide
• CAS NO: 1220123-33-0
• Molecular Weight: 274.406
• Mol File: 1220123-33-0.mol

Chemical Properties

• CAS DataBase Reference: N-((1S,3R)-3-(ethylamino)-2,2,3-trimethylcyclopentyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1S,3R)-3-(ethylamino)-2,2,3-trimethylcyclopentyl)benzamide(1220123-33-0)
• EPA Substance Registry System: N-((1S,3R)-3-(ethylamino)-2,2,3-trimethylcyclopentyl)benzamide(1220123-33-0)

Safety Data

• Hazardous Substances Data: 1220123-33-0(Hazardous Substances Data)

Upstream product

• 116481-14-2 (1R,3S)-1,2,2-trimethyl-1,3-cyclopentanediamine 
• 124-83-4 D-(+)-camphoric acid 
• 75-03-6 ethyl iodide 

Relevant articles and documents

Novel tridentate ligands derived from (+)-camphoric acid for enantioselective ethylation of aromatic aldehydes

Novel tridentate ligands were prepared from (+)-camphoric acid, using simple synthetic sequences. The synthesized ligands were used in enantioselective ethylations of benzaldehydes, showing enantioselectivities up to 92%, at room temperature. Extending th

Reactivity of Copper(I) Complexes Containing Ligands Derived from (1S,3R)-Camphoric Acid with Dioxygen

Amine derivatives prepared from camphoric acid were used as ligands for the synthesis of corresponding copper(I) complexes. Their reactivity towards dioxygen was analyzed. The formation of a short-lived bis(μ-oxido)copper complex was spectroscopically observed during the reaction of the copper(I) complex with (1R, 3S)-N1,N1,N3,N3-Tetramethyl-1,2,2-trimethylcyclopentane-1,3-diamine as a ligand. Furthermore, a regioselective demethylation of the ligand system was detected. Deuteration of the methyl groups of the ligand allowed crystallization and characterization of the bis(μ-oxido)copper complex. Derivatives of the ligand with pyridine residues caused suppression of the reactivity of the corresponding copper(I) complexes towards dioxygen. Additionally, the ligand system could be modified for intramolecular oxygenation reactions with benzaldehyde that led to the formation of salicylaldehyde, a selective hydroxylation in ortho position.

Enantioselective ethylation of aldehydes with 1,3-N-donor ligands derived from (+)-camphoric acid

Derivatives of (+)-camphoric acid were prepared by a short and simple synthetic sequence and proved to be excellent ligands for the enantioselective ethylation of benzaldehyde with diethylzinc, with ees of up to 96% being obtained. The most efficient liga