1220193-97-4Relevant academic research and scientific papers
Relay catalysis: Combined metal catalyzed oxidation and asymmetric iminium catalysis for the synthesis of Bi- and tricyclic chromenes
Rueping, Magnus,Dufour, Jeremy,Maji, Modhu Sudan
supporting information; experimental part, p. 3406 - 3408 (2012/04/18)
A catalytic asymmetric oxidative iminium-allenamine cascade allows the use of propargyl alcohols as stable substrates and yields valuable chiral bicyclic 4H-chromenes. A subsequent Michael addition-condensation domino reaction provides complex tricyclic 4H-chromenes in a highly enantioselective fashion.
Iminium-allenamine cascade catalysis: One-pot access to chiral 4Hchromenes by a highly enantioselective michael-michael sequence
Zhang, Xinshuai,Zhang, Shilei,Wang, Wei
supporting information; experimental part, p. 1481 - 1484 (2010/05/18)
Chemical Equation Presented Taking the Michael-Michael: A cascade Michael-Michael reaction of aryl or alkyl alkynals, involving an unprecedented iminium - allenamine sequence, is efficiently catalyzed by a chiral diphenylprolinol TBDMS ether, and affords highly functionalized 4H-chromenes in high yields. TBDMS = tert-butyldimethylsilyl.
