3156-43-2

Basic information

• Product Name: TRANS-2-HYDROXY-BETA-NITROSTYRENE 97
• Synonyms: TRANS-2-HYDROXY-BETA-NITROSTYRENE 97;trans-2-hydroxy-β-nitrostyrene;1-Hydroxy-2-(2-nitrovinyl)benzene, 2-(2-Hydroxyphenyl)nitroethene, trans-2-(2-Nitrovinyl)phenol;2-(2-Nitroethenyl)phenol;2-Hydroxy-β-nitrostyrene;NSC 170698;(E)-2-(2-nitrovinyl)phenol;trans-2-Hydroxy-beta-nitrostyrene 97%
• CAS NO: 3156-43-2
• Molecular Formula: C₈H₇NO₃
• Molecular Weight: 165.147
• Product Categories: Acyclic;Alkenes;Building Blocks;Chemical Synthesis;Organic Building Blocks
• Mol File: 3156-43-2.mol
• Article Data: 35

Chemical Properties

• Boiling Point: 320.2°Cat760mmHg
• Flash Point: 145.1°C
• Appearance: /
• Density: 1.32g/cm³
• Vapor Pressure: 0.000172mmHg at 25°C
• Refractive Index: 1.646
• CAS DataBase Reference: TRANS-2-HYDROXY-BETA-NITROSTYRENE 97(CAS DataBase Reference)
• NIST Chemistry Reference: TRANS-2-HYDROXY-BETA-NITROSTYRENE 97(3156-43-2)
• EPA Substance Registry System: TRANS-2-HYDROXY-BETA-NITROSTYRENE 97(3156-43-2)

Safety Data

• Hazard Codes: Xn,N
• Statements: 22-36/38-50
• Safety Statements: 26-36/37-60-61
• RIDADR: UN 3077 9/PG 3
• WGK Germany: 2
• Hazardous Substances Data: 3156-43-2(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 3156-43-2 differently. You can refer to the following data:
1. Reactant for:? ;Michael-acetalization reactions1? ;Organocatalytic stereoselective Baylis-Hillman-type reactions with Hagemann′s esters2? ;Catalyst-free aqueous-mediated conjugate addition reactions3
2. Reactant for:Michael-acetalization reactionsOrganocatalytic stereoselective Baylis-Hillman-type reactions with Hagemann′s estersCatalyst-free aqueous-mediated conjugate addition reactions

InChI:InChI=1/C8H7NO3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H

Upstream product

• 75-52-5 nitromethane 
• 90-02-8 salicylaldehyde 
• 67-56-1 methanol 
• 89-95-2 2-methyl-benzyl alcohol 
• 1629184-90-2 (E)-2-[1-(2-hydroxybenzylideneamino)-2-nitroethyl]phenol 

Downstream Products

• 126814-18-4 ethyl 2-ethoxycarbonyl-3-(2-hydroxyphenyl)-4-nitrobutyrate 
• 2039-66-9 o-tyramine 
• 87745-35-5 Methyl-carbamic acid 2-((E)-2-nitro-vinyl)-phenyl ester 
• 1122077-33-1 C₂₆H₁₉Br₂NO₄ 
• 1221276-66-9 C₂₆H₂₆N₂O₃ 
• 1221276-57-8 5-(nitromethyl)-1-phenyl-2,3,4,4a,5,10a-hexahydro-1H-chromeno[2,3-b]pyridine 
• 1221276-61-4 C₂₁H₂₄N₂O₃ 
• 1221276-59-0 C₂₀H₂₂N₂O₃ 
• 1221276-65-8 C₁₉H₁₉ClN₂O₃ 
• 1221276-60-3 C₁₉H₁₉BrN₂O₃ 
• 1221276-58-9 C₂₀H₂₂N₂O₄ 
• 1221276-62-5 C₂₀H₂₂N₂O₃ 
• 1221276-63-6 C₁₉H₁₉ClN₂O₃ 
• 1255037-09-2 (E)-2-(3-hydroxy-2-nitroprop-1-enyl)phenol 

Relevant articles and documents

Synthesis, characterization and crystal structure of trans-2-(2- Hydroxyphenyl)-1-nitroethylene

The nitroalkene compound, namely trans-2-(2-hydroxyphenyl)-1-nitroethylene (I), has been successfully synthesized from the condensation of 2-hydroxybenzaladehyde with nitromethane. It was characterized by elemental analysis, 1H NMR spectrum and single-cry

Green sustainable approach for carbon–carbon bond-forming reactions using FeNPs/DETA@rGO nano-catalyst

We have fabricated eccentric highly persuasive bifunctional FeNPs/DETA@rGO (where DETA = diethylenetriamine) nano-catalyst with a dual activation mechanism by presenting aliphatic amine on the basal and/or edges sites offering a base characteristic and Fe

Strategies towards potent trypanocidal drugs: Application of Rh-catalyzed [2?+?2?+?2] cycloadditions, sulfonyl phthalide annulation and nitroalkene reactions for the synthesis of substituted quinones and their evaluation against Trypanosoma cruzi

Rhodium-catalyzed [2 + 2 + 2] cycloadditions, sulfonyl phthalide annulations and nitroalkene reactions have been employed for the synthesis of 56 quinone-based compounds. These were evaluated against Trypanosoma cruzi, the parasite that causes Chagas disease. The reactions described here are part of a program that aims to utilize modern, versatile and efficient synthetic methods for the one or two step preparation of trypanocidal compounds. We have identified 9 compounds with potent activity against the parasite; 3 of these were 30-fold more potent than benznidazole (Bz), a drug used for the treatment of Chagas disease. This article provides a comprehensive outline of reactions involving over 120 compounds aimed at the discovery of new quinone-based frameworks with activity against T. cruzi.

Enantioselective dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman carbonates

The phosphine-catalyzed asymmetric dearomative [3+2] cycloaddition of 2-nitrobenzofurans with aldehyde-derived Morita-Baylis-Hillman (MBH) carbonates or allenoate was developed. The reaction with MBH carbonates resulted in a series of cyclopentabenzofurans containing three contiguous stereocenters with good to high yields, diastereoselectivities and enantioselectivities. The use of allenoate also gave the target product with moderate enantioselectivity.