1220307-41-4Relevant articles and documents
A facile one-pot transformation of baylis-hillman adducts into unsymmetrical disubstituted maleimide and maleic anhydride frameworks: A facile synthesis of himanimide A
Basavaiah, Deevi,Devendar, Badugu,Aravindu, Kunche,Veerendhar, Ainelly
supporting information; experimental part, p. 2031 - 2035 (2010/07/05)
Unsymmetrical, disubstituted maleimide and maleic anhydride frameworks have been accessed from Baylis-Hillman adducts in an operationally simple three-step (FriedelCrafts reaction, selective hydrolysis and cyclization), one-pot strategy. This strategy has been successfully extended to the synthesis of a representative bioactive compound, himanimide A (see scheme). (Chemical Equation Representation).