464895-13-4Relevant academic research and scientific papers
A facile one-pot transformation of baylis-hillman adducts into unsymmetrical disubstituted maleimide and maleic anhydride frameworks: A facile synthesis of himanimide A
Basavaiah, Deevi,Devendar, Badugu,Aravindu, Kunche,Veerendhar, Ainelly
supporting information; experimental part, p. 2031 - 2035 (2010/07/05)
Unsymmetrical, disubstituted maleimide and maleic anhydride frameworks have been accessed from Baylis-Hillman adducts in an operationally simple three-step (FriedelCrafts reaction, selective hydrolysis and cyclization), one-pot strategy. This strategy has been successfully extended to the synthesis of a representative bioactive compound, himanimide A (see scheme). (Chemical Equation Representation).
Iron-catalyzed carbonylation as a key step in the short and efficient syntheses of himanimide A and B
Prateeptongkum, Saisuree,Driller, Katrin Marie,Jackstell, Ralf,Beller, Matthias
, p. 2173 - 2176 (2011/06/19)
Isn't it iron-ic: An iron-catalyzed [2+1+1+1]-annulation strategy is used for the construction of five-membered maleimides, which are building blocks for naturally occurring himanimides A and B.
