122033-75-4

Upstream product

• 5292-42-2 methyl-2,3,4,5-tetrafluoro benzoate 
• 715-37-7 methyl 4-amino-2,3,5,6-tetrafluorobenzoate 
• 138724-32-0 methyl 4-amino-2,3,5-trifluorobenzoate 

Relevant academic research and scientific papers

Four-ring-fused compound as well as preparation method and application thereof

The invention discloses a compound shown as a formula (I), an optical isomer and pharmacologically acceptable salts thereof, and application of the compound as a KRAS inhibitor.

FUSED TRICYCLIC COMPOUNDS USEFUL AS ANTICANCER AGENTS

The specification relates to compounds of Formula (A) and pharmaceutically acceptable salts thereof. The specification also relates to processes and intermediates used for their preparation, pharmaceutical compositions containing them and their use in the treatment of cell proliferative disorders.